Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2133160..2133431 Replicon chromosome
Accession NZ_CP085183
Organism Escherichia coli strain EC7518

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2133290..2133393 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2133160..2133431 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LIN51_RS10390 2129715..2130377 - 663 WP_000944256.1 exodeoxyribonuclease X -
LIN51_RS10395 2130401..2131057 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
LIN51_RS10400 2131159..2131389 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LIN51_RS10405 2131528..2131902 + 375 WP_000204699.1 CopC domain-containing protein YobA -
LIN51_RS10410 2131906..2132778 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
LIN51_RS10415 2132791..2133132 + 342 WP_000976492.1 YebY family protein -
- 2133160..2133431 - 272 - - Antitoxin
- 2133290..2133393 + 104 - - Toxin
LIN51_RS10420 2133528..2134184 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
LIN51_RS10425 2134185..2134376 - 192 WP_001296140.1 YebW family protein -
LIN51_RS10430 2134481..2134717 - 237 WP_001295499.1 YebV family protein -
LIN51_RS10435 2134835..2136274 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T220538 NZ_CP085183:2133290-2133393 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT220538 NZ_CP085183:c2133431-2133160 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References