Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 245771..246311 Replicon plasmid pDSM109990_a
Accession NZ_CP085145
Organism Sulfitobacter dubius strain DSM 109990

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag DSM109990_RS17345 Protein ID WP_243263336.1
Coordinates 246018..246311 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag DSM109990_RS17340 Protein ID WP_243263334.1
Coordinates 245771..246028 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSM109990_RS17320 (DSM109990_03514) 241365..242429 - 1065 WP_243263330.1 NAD(P)-dependent oxidoreductase -
DSM109990_RS17325 (DSM109990_03515) 242426..243148 - 723 WP_243263531.1 ABC transporter permease -
DSM109990_RS17330 (DSM109990_03516) 243304..243966 - 663 WP_243263532.1 TetR family transcriptional regulator -
DSM109990_RS17335 (DSM109990_03517) 244145..245140 + 996 WP_243263332.1 ABC transporter substrate-binding protein -
DSM109990_RS17340 (DSM109990_03518) 245771..246028 + 258 WP_243263334.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
DSM109990_RS17345 (DSM109990_03519) 246018..246311 + 294 WP_243263336.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DSM109990_RS17350 (DSM109990_03520) 246336..246545 - 210 WP_243263337.1 hypothetical protein -
DSM109990_RS17355 (DSM109990_03522) 246796..247821 + 1026 WP_243263311.1 IS110 family transposase -
DSM109990_RS17360 (DSM109990_03523) 248204..249229 + 1026 WP_243263311.1 IS110 family transposase -
DSM109990_RS17365 (DSM109990_03524) 249545..250303 - 759 WP_243263339.1 IS21-like element helper ATPase IstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..284454 284454


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-92)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11321.83 Da        Isoelectric Point: 5.0965

>T220524 WP_243263336.1 NZ_CP085145:246018-246311 [Sulfitobacter dubius]
MQDKPYALSPLAEIDLEEIWFYTFQKWSLAQADSYHRDLIATFEGLVSGTKRGREVDVRPDYLKCPVGSHMIYFRDSGDQ
MEVIRVLHQRQDATLNL

Download         Length: 294 bp

>T220524 NZ_CP117054:c793397-793095 [Vibrio harveyi]
ATGGCTGAAGTAATCTGGACTGAACCAGCGTTATCTGACCTCAATGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTACAAACGATCTTCTCCAAAGTCGAACGCCTACGAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGAGCTAGAGCATTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATGCGTGCAGAGAGAGATTTGCGTAAGTTCTTGTTGGGTAAGCAATAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9222.26 Da        Isoelectric Point: 7.4705

>AT220524 WP_243263334.1 NZ_CP085145:245771-246028 [Sulfitobacter dubius]
MPRNTSVTLGTHFSDFIGEQVQTGRYGSASDVVRAGLRLLEEHETKVRALQDALIAGEQSGTPRSFDSDAFLSRMHAKHA
AKHAG

Download         Length: 258 bp

>AT220524 NZ_CP117054:c793642-793385 [Vibrio harveyi]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATCCTCGCCGATCTCCACGACACCAAAGAACCAGT
GTTAATTACCGAGCATGGTAAGCCATCTGCGTATCTAGTTGATGTTGATGACTACGAATTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGATGGTAAAGTTGTAAGTCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References