Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3776496..3777406 Replicon chromosome
Accession NZ_CP085143
Organism Halomonas sp. NyZ770

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LG409_RS17400 Protein ID WP_227407265.1
Coordinates 3776942..3777406 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LG409_RS17395 Protein ID WP_039178599.1
Coordinates 3776496..3776945 (+) Length 150 a.a.

Genomic Context

LG409_RS17370LG409_RS17375LG409_RS17380LG409_RS17395LG409_RS17400LG409_RS17385LG409_RS17390LG409_RS17405LG409_RS17410LG409_RS17415LG409_RS17420
Location: 3771783..3772121 (339 bp)
Type: Others
Protein ID: WP_096921856.1
Location: 3772314..3772709 (396 bp)
Type: Others
Protein ID: WP_227407263.1
Location: 3772970..3774334 (1365 bp)
Type: Others
Protein ID: WP_227407264.1
Location: 3776496..3776945 (450 bp)
Type: Antitoxin
Protein ID: WP_039178599.1
Location: 3776942..3777406 (465 bp)
Type: Toxin
Protein ID: WP_227407265.1
Location: 3774356..3774901 (546 bp)
Type: Others
Protein ID: WP_081193388.1
Location: 3774920..3776284 (1365 bp)
Type: Others
Protein ID: WP_039178596.1
Location: 3777423..3778130 (708 bp)
Type: Others
Protein ID: WP_227407266.1
Location: 3778130..3778966 (837 bp)
Type: Others
Protein ID: WP_016915368.1
Location: 3778963..3780105 (1143 bp)
Type: Others
Protein ID: WP_016915369.1
Location: 3780112..3781719 (1608 bp)
Type: Others
Protein ID: WP_227407267.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LG409_RS17370 (LG409_17370)3771783..3772121+339WP_096921856.1hypothetical protein-
LG409_RS17375 (LG409_17375)3772314..3772709+396WP_227407263.1DUF2946 domain-containing protein-
LG409_RS17380 (LG409_17380)3772970..3774334+1365WP_227407264.1PepSY domain-containing protein-
LG409_RS17385 (LG409_17385)3774356..3774901-546WP_081193388.1copper chaperone PCu(A)C-
LG409_RS17390 (LG409_17390)3774920..3776284-1365WP_039178596.1diguanylate cyclase-
LG409_RS17395 (LG409_17395)3776496..3776945+450WP_039178599.1DUF2384 domain-containing proteinAntitoxin
LG409_RS17400 (LG409_17400)3776942..3777406+465WP_227407265.1RES family NAD+ phosphorylaseToxin
LG409_RS17405 (LG409_17405)3777423..3778130-708WP_227407266.1urea ABC transporter ATP-binding subunit UrtE-
LG409_RS17410 (LG409_17410)3778130..3778966-837WP_016915368.1urea ABC transporter ATP-binding protein UrtD-
LG409_RS17415 (LG409_17415)3778963..3780105-1143WP_016915369.1urea ABC transporter permease subunit UrtC-
LG409_RS17420 (LG409_17420)3780112..3781719-1608WP_227407267.1urea ABC transporter permease subunit UrtB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(7-149)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(31-90)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 16897.23 Da        Isoelectric Point: 4.4996

>T220519 WP_227407265.1 NZ_CP085143:3776942-3777406 [Halomonas sp. NyZ770]
MSEVTAFRLVKRKFQETAFDGDGARLYGGRWNSPGNACVYVASSESLALLEIMVHLESYRLLNAYALLRLTLPKQSILSV
GTEDLPENWREAPAPAETADLGDGWLASGQSLALALPSVVVPRELNYMLNPAHPLFEQAVASAEELPFQPDPRL

Download         Length: 465 bp

>T220519 NZ_CP117053:4283556-4283813 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16553.99 Da        Isoelectric Point: 10.2591

>AT220519 WP_039178599.1 NZ_CP085143:3776496-3776945 [Halomonas sp. NyZ770]
MAATFSQYQPTKAVASGYWQQIGLPARGRKLHELLHEGVEYRVYPRLAKVSGIEQKALARYVDIPSATLSRRAKSGRFKM
AESDRLYRFAELFKAALDLFEGDAEGARAWLLKPNAGLGGRRPVEMSATSAEYQTVLNLIGRLEHGVSV

Download         Length: 450 bp

>AT220519 NZ_CP117053:4283825-4284370 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References