Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii(toxin)
Location 2836767..2837412 Replicon chromosome
Accession NZ_CP085135
Organism Mesorhizobium sp. PAMC28654

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag LGH82_RS33340 Protein ID WP_264484385.1
Coordinates 2836963..2837412 (+) Length 150 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag LGH82_RS14045 Protein ID WP_227349759.1
Coordinates 2836767..2836973 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGH82_RS14020 (LGH82_14020) 2833151..2833972 + 822 WP_227345040.1 IS5 family transposase -
LGH82_RS14025 (LGH82_14025) 2834078..2834599 - 522 WP_227349026.1 hypothetical protein -
LGH82_RS14030 (LGH82_14030) 2834737..2835363 - 627 WP_227349027.1 hypothetical protein -
LGH82_RS14035 (LGH82_14035) 2835783..2836214 - 432 WP_227349028.1 XRE family transcriptional regulator -
LGH82_RS14045 (LGH82_14045) 2836767..2836973 + 207 WP_227349759.1 hypothetical protein Antitoxin
LGH82_RS33340 2836963..2837412 + 450 WP_264484385.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LGH82_RS33345 2837409..2837678 + 270 WP_264484400.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
LGH82_RS14055 (LGH82_14055) 2838056..2839045 - 990 WP_227349029.1 LysR family transcriptional regulator -
LGH82_RS14060 (LGH82_14060) 2839358..2840428 + 1071 WP_227349030.1 sugar ABC transporter substrate-binding protein -
LGH82_RS14065 (LGH82_14065) 2840587..2842119 + 1533 WP_227349581.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 150 a.a.        Molecular weight: 16475.81 Da        Isoelectric Point: 8.2549

>T220510 WP_264484385.1 NZ_CP085135:2836963-2837412 [Mesorhizobium sp. PAMC28654]
MARELRNVGASVRARLLDRAREERSDFQLLLTRYALERLLYRLSISAERERFLLKGAMLFAAWLDNPSRPTRDLDLLGSG
DAGVATMVECFQTICSTPVQNDGVKFDVAGLTAEPIRYEAEYAGVRVSTAATMPARACPSRSTSASATW

Download         Length: 450 bp

>T220510 NZ_CP117053:c2541941-2541765 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATAGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7706.87 Da        Isoelectric Point: 7.9777

>AT220510 WP_227349759.1 NZ_CP085135:2836767-2836973 [Mesorhizobium sp. PAMC28654]
VPVFEPAKAIVDCFRYRNKIGLDIALEGLREGPWTRQVTPDQLWKFAQSGRVWSVTRPYVEAMVADGA

Download         Length: 207 bp

>AT220510 NZ_CP117053:c2541719-2541303 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References