Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 448300..448939 Replicon chromosome
Accession NZ_CP085083
Organism Acinetobacter vivianii strain KJ-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LF296_RS02180 Protein ID WP_272655369.1
Coordinates 448544..448939 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N8W7X1
Locus tag LF296_RS02175 Protein ID WP_004775865.1
Coordinates 448300..448557 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LF296_RS02150 (LF296_02150) 443324..443689 + 366 WP_004641032.1 50S ribosomal protein L17 -
LF296_RS02155 (LF296_02155) 443879..444376 + 498 WP_272655367.1 GNAT family N-acetyltransferase -
LF296_RS02160 (LF296_02160) 444767..446257 + 1491 WP_004775870.1 NAD(P)/FAD-dependent oxidoreductase -
LF296_RS02165 (LF296_02165) 446384..446887 + 504 WP_272655368.1 DUF2059 domain-containing protein -
LF296_RS02170 (LF296_02170) 446939..448111 - 1173 WP_004775867.1 acyl-CoA dehydrogenase family protein -
LF296_RS02175 (LF296_02175) 448300..448557 + 258 WP_004775865.1 succinate dehydrogenase assembly factor 2 Antitoxin
LF296_RS02180 (LF296_02180) 448544..448939 + 396 WP_272655369.1 hypothetical protein Toxin
LF296_RS02185 (LF296_02185) 449147..449350 + 204 WP_004775862.1 hypothetical protein -
LF296_RS02190 (LF296_02190) 449709..450809 + 1101 WP_004775861.1 hypothetical protein -
LF296_RS02195 (LF296_02195) 450887..451465 + 579 WP_004775858.1 rhombosortase -
LF296_RS02200 (LF296_02200) 451649..453853 + 2205 WP_005259810.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 15924.77 Da        Isoelectric Point: 7.8940

>T220416 WP_272655369.1 NZ_CP085083:448544-448939 [Acinetobacter vivianii]
MFTANRVFELQYSRFSIALQLFILLLIVSLTYSLLSLVLWLSNCFLLALSWFLFLKQPRLKRFEYLDQQEWSFEFYDSSL
PIQCHKIEKIIDHQAYIVLYFSDPEHKNFIIWWDQLSLLQWKNLKLHAKLA

Download         Length: 396 bp

>T220416 NZ_CP117016:c5186660-5186553 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10128.56 Da        Isoelectric Point: 4.4798

>AT220416 WP_004775865.1 NZ_CP085083:448300-448557 [Acinetobacter vivianii]
MSDEMTLEERKVVYRARRGLKEIDVYFDPYVKSYYLTADPAEKALFAELVDQEDPDLLDWFMEVGEPPRTELKEFILKLK
HYVHG

Download         Length: 258 bp

>AT220416 NZ_CP117016:5186713-5186774 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0B0KPM6

References