Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2956653..2956804 Replicon chromosome
Accession NZ_CP085080
Organism Enterobacter cloacae strain ECl_1.VN

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2956666..2956769 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2956653..2956804 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH408_RS13895 (LH408_13895) 2952928..2954370 + 1443 WP_094915471.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LH408_RS13900 (LH408_13900) 2954476..2954715 + 240 WP_013096113.1 YebV family protein -
LH408_RS13905 (LH408_13905) 2954749..2955394 - 646 Protein_2722 protein-serine/threonine phosphatase -
LH408_RS13910 (LH408_13910) 2955561..2956502 + 942 WP_038419912.1 VirK/YbjX family protein -
- 2956653..2956804 + 152 - - Antitoxin
- 2956666..2956769 - 104 - - Toxin
LH408_RS13915 (LH408_13915) 2956909..2957247 - 339 WP_128310471.1 YebY family protein -
LH408_RS13920 (LH408_13920) 2957264..2958133 - 870 WP_226834718.1 copper homeostasis membrane protein CopD -
LH408_RS13925 (LH408_13925) 2958135..2958506 - 372 WP_013096103.1 CopC domain-containing protein YobA -
LH408_RS13930 (LH408_13930) 2958644..2958874 + 231 WP_013096102.1 DNA polymerase III subunit theta -
LH408_RS13935 (LH408_13935) 2958984..2959634 + 651 WP_226834719.1 carbon-nitrogen hydrolase family protein -
LH408_RS13940 (LH408_13940) 2959658..2960320 + 663 WP_020690817.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2947553..2978908 31355


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T220397 NZ_CP085080:c2956769-2956666 [Enterobacter cloacae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 152 bp

>AT220397 NZ_CP085080:2956653-2956804 [Enterobacter cloacae]
CTTTCAATCAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGC
TAAAAGTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References