Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 487436..487952 Replicon chromosome
Accession NC_009436
Organism Enterobacter sp. 638

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ENT638_RS02290 Protein ID WP_012015848.1
Coordinates 487668..487952 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ENT638_RS02285 Protein ID WP_012015847.1
Coordinates 487436..487678 (+) Length 81 a.a.

Genomic Context

ENT638_RS02270ENT638_RS02275ENT638_RS02280ENT638_RS02285ENT638_RS02290ENT638_RS02295ENT638_RS02300ENT638_RS02305
Location: 483382..484122 (741 bp)
Type: Others
Protein ID: WP_012015844.1
Location: 484283..485428 (1146 bp)
Type: Others
Protein ID: WP_012015845.1
Location: 485448..487358 (1911 bp)
Type: Others
Protein ID: WP_012015846.1
Location: 487436..487678 (243 bp)
Type: Antitoxin
Protein ID: WP_012015847.1
Location: 487668..487952 (285 bp)
Type: Toxin
Protein ID: WP_012015848.1
Location: 487954..488418 (465 bp)
Type: Others
Protein ID: WP_012015849.1
Location: 488578..490716 (2139 bp)
Type: Others
Protein ID: WP_012015850.1
Location: 491092..492747 (1656 bp)
Type: Others
Protein ID: WP_012015851.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ENT638_RS02270483382..484122+741WP_012015844.1KDGP aldolase family protein-
ENT638_RS02275484283..485428+1146WP_012015845.1lactonase family protein-
ENT638_RS02280485448..487358+1911WP_012015846.1BglG family transcription antiterminator-
ENT638_RS02285487436..487678+243WP_012015847.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
ENT638_RS02290487668..487952+285WP_012015848.1type II toxin-antitoxin system RelE/ParE family toxinToxin
ENT638_RS02295487954..488418-465WP_012015849.1anaerobic ribonucleoside-triphosphate reductase-activating protein-
ENT638_RS02300488578..490716-2139WP_012015850.1anaerobic ribonucleoside-triphosphate reductase-
ENT638_RS02305491092..492747-1656WP_012015851.1alpha,alpha-phosphotrehalase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11018.04 Da        Isoelectric Point: 10.3778

>T22038 WP_012015848.1 NC_009436:487668-487952 [Enterobacter sp. 638]
MTYELAFDPRALKEWYKLGDTVRAQFKKKLAQVLAEPRIKSARLTDLPDCYKIKLRASGYRLVYQVRDDVVMVFVIAVGK
REKLVVYHDANKRL

Download         Length: 285 bp

>T22038 NC_009436:487668-487952 [Enterobacter sp. 638]
ATGACTTATGAACTCGCGTTCGATCCGCGTGCGCTTAAAGAGTGGTACAAGCTGGGCGATACGGTAAGAGCTCAGTTTAA
GAAGAAACTAGCGCAAGTGCTGGCGGAACCCCGGATTAAATCTGCCCGTTTAACGGATTTGCCTGACTGCTACAAAATCA
AGCTAAGAGCATCTGGCTATCGTCTGGTTTACCAGGTGCGTGATGACGTGGTGATGGTCTTCGTCATAGCGGTAGGGAAA
CGCGAGAAATTAGTCGTTTATCATGACGCCAATAAACGACTGTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8988.28 Da        Isoelectric Point: 4.5203

>AT22038 WP_012015847.1 NC_009436:487436-487678 [Enterobacter sp. 638]
MATLNVRLDDKLKNEAYAVLEKLNLTPTEAVRLLFQYVAETGRMPVKTVTISDSEEALIQTVRERLNSPQNGIQVSLDDL

Download         Length: 243 bp

>AT22038 NC_009436:487436-487678 [Enterobacter sp. 638]
ATGGCAACGCTGAACGTCCGTCTGGACGATAAACTTAAAAATGAGGCTTACGCGGTGCTGGAAAAACTTAACCTTACCCC
GACAGAAGCGGTGCGCCTGCTATTCCAGTATGTGGCAGAAACCGGACGTATGCCGGTGAAGACGGTCACGATTAGCGATA
GCGAAGAAGCCCTAATCCAAACCGTCCGCGAGCGGCTAAATAGCCCGCAAAATGGTATCCAGGTTAGTTTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References