Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 60386..61122 Replicon plasmid pENTE01
Accession NC_009425
Organism Enterobacter sp. 638

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag ENT638_RS21710 Protein ID WP_011906517.1
Coordinates 60386..60868 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag ENT638_RS21715 Protein ID WP_011906518.1
Coordinates 60856..61122 (-) Length 89 a.a.

Genomic Context

ENT638_RS23260ENT638_RS21730ENT638_RS21695ENT638_RS21700ENT638_RS21710ENT638_RS21715ENT638_RS21720
Location: 61829..62008 (180 bp)
Type: Others
Protein ID: WP_063925957.1
Location: 62692..63126 (435 bp)
Type: Others
Protein ID: WP_011906519.1
Location: 56798..58195 (1398 bp)
Type: Others
Protein ID: WP_011906515.1
Location: 58466..59671 (1206 bp)
Type: Others
Protein ID: WP_011906516.1
Location: 60386..60868 (483 bp)
Type: Toxin
Protein ID: WP_011906517.1
Location: 60856..61122 (267 bp)
Type: Antitoxin
Protein ID: WP_011906518.1
Location: 61244..61744 (501 bp)
Type: Others
Protein ID: WP_049759462.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ENT638_RS2169556798..58195-1398WP_011906515.1hypothetical protein-
ENT638_RS2170058466..59671-1206WP_011906516.1VWA domain-containing protein-
ENT638_RS2171060386..60868-483WP_011906517.1GNAT family N-acetyltransferaseToxin
ENT638_RS2171560856..61122-267WP_011906518.1DUF1778 domain-containing proteinAntitoxin
ENT638_RS2172061244..61744-501WP_049759462.1hypothetical protein-
ENT638_RS2326061829..62008+180WP_063925957.1thioredoxin family protein-
ENT638_RS2173062692..63126+435WP_011906519.1universal stress protein UspF-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..157749157749


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-151)

Antitoxin

Vibrio phage ICP1, Orf50

(2-87)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17670.32 Da        Isoelectric Point: 9.1157

>T22033 WP_011906517.1 NC_009425:c60868-60386 [Enterobacter sp. 638]
VGRVTAPEPLSSTHQLAEFVSGETVLDDWLKQRGLKNQAFRTTRTFVVCKTDMKQVAGFYSLATGSVNHVDSTGSLRHNM
PDPIPVIILARLAVDVSFRGKGIGADLLQDAVLRCYRVAENIGVRAIMVHAMTEEAKSFYVHHGFTASQTQERTLFLKLP

Download         Length: 483 bp

>T22033 NC_009425:c60868-60386 [Enterobacter sp. 638]
GTGGGACGTGTAACAGCACCAGAACCGTTATCCAGTACCCATCAACTGGCTGAGTTCGTCAGCGGGGAGACTGTGCTCGA
TGACTGGCTTAAACAGAGAGGGTTAAAAAATCAGGCATTCAGAACCACCCGTACGTTTGTGGTTTGTAAAACAGACATGA
AACAGGTTGCCGGTTTTTATTCTCTGGCCACCGGCAGTGTTAACCATGTGGATTCTACGGGAAGCCTCAGGCACAATATG
CCCGATCCAATTCCCGTAATTATACTTGCTCGCCTGGCGGTCGATGTTTCATTCCGTGGAAAAGGGATCGGGGCTGATTT
ACTGCAAGATGCAGTTTTACGCTGTTACCGTGTAGCTGAGAACATTGGTGTCCGTGCGATTATGGTTCATGCAATGACTG
AAGAAGCCAAAAGCTTTTATGTCCACCACGGTTTTACTGCATCGCAAACGCAGGAGCGGACGCTGTTTCTTAAGCTTCCA
TAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10099.51 Da        Isoelectric Point: 4.5010

>AT22033 WP_011906518.1 NC_009425:c61122-60856 [Enterobacter sp. 638]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAEHVILDRRVFNFNDEQYAEFIDMLDAPVADDPAIDKLL
ARKPQWDV

Download         Length: 267 bp

>AT22033 NC_009425:c61122-60856 [Enterobacter sp. 638]
ATGAAATCCGATGTTCAACTCAATCTTAGAGCCAAGGAATCTCAACGAGCACTCATTGATGCTGCAGCAGAGATTCTTCA
TAAATCACGCACAGACTTCATCCTGGAAATGGCATGCCAGGCTGCGGAGCATGTGATCCTCGATCGTCGCGTATTCAATT
TTAACGATGAGCAGTATGCAGAGTTCATCGATATGCTCGATGCACCCGTTGCAGATGACCCTGCCATTGATAAACTTCTG
GCCAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References