Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2604270..2604541 Replicon chromosome
Accession NZ_CP085060
Organism Escherichia coli strain P30_L1_05.20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2604308..2604411 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2604270..2604541 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH369_RS12545 2601427..2602866 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LH369_RS12550 2602984..2603220 + 237 WP_001295499.1 YebV family protein -
LH369_RS12555 2603325..2603516 + 192 WP_000457842.1 YebW family protein -
LH369_RS12560 2603517..2604173 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2604270..2604541 + 272 - - Antitoxin
- 2604308..2604411 - 104 - - Toxin
LH369_RS12565 2604569..2604910 - 342 WP_000976476.1 YebY family protein -
LH369_RS12570 2604923..2605795 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
LH369_RS12575 2605799..2606173 - 375 WP_000168747.1 CopC domain-containing protein YobA -
LH369_RS12580 2606312..2606542 + 231 WP_000916763.1 DNA polymerase III subunit theta -
LH369_RS12585 2606644..2607300 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LH369_RS12590 2607324..2607986 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T220264 NZ_CP085060:c2604411-2604308 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT220264 NZ_CP085060:2604270-2604541 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References