Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2070759..2071030 Replicon chromosome
Accession NZ_CP085056
Organism Escherichia coli strain P24_WM1_05.20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2070889..2070992 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2070759..2071030 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHK10_RS09990 2067314..2067976 - 663 WP_000944256.1 exodeoxyribonuclease X -
LHK10_RS09995 2068000..2068656 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LHK10_RS10000 2068758..2068988 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LHK10_RS10005 2069127..2069501 + 375 WP_000204699.1 CopC domain-containing protein YobA -
LHK10_RS10010 2069505..2070377 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
LHK10_RS10015 2070390..2070731 + 342 WP_000976492.1 YebY family protein -
- 2070759..2071030 - 272 - - Antitoxin
- 2070889..2070992 + 104 - - Toxin
LHK10_RS10020 2071127..2071783 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LHK10_RS10025 2071784..2071975 - 192 WP_001296140.1 YebW family protein -
LHK10_RS10030 2072080..2072316 - 237 WP_001295499.1 YebV family protein -
LHK10_RS10035 2072434..2073873 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T220235 NZ_CP085056:2070889-2070992 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT220235 NZ_CP085056:c2071030-2070759 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References