Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1980373..1980518 Replicon chromosome
Accession NZ_CP084986
Organism Klebsiella pneumoniae strain KP18-2110-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1980409..1980511 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1980373..1980518 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH404_RS09680 1975503..1977563 + 2061 WP_004151449.1 oligopeptidase B -
LH404_RS09685 1977567..1978226 - 660 WP_021440386.1 exodeoxyribonuclease X -
LH404_RS09690 1978305..1978535 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LH404_RS09695 1978648..1979022 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LH404_RS09700 1979026..1979895 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LH404_RS09705 1979912..1980250 + 339 WP_002911404.1 YebY family protein -
- 1980373..1980518 - 146 - - Antitoxin
- 1980409..1980511 + 103 - - Toxin
LH404_RS09710 1980886..1981029 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LH404_RS09715 1981134..1982102 - 969 WP_004151446.1 VirK/YbjX family protein -
LH404_RS09720 1982259..1982912 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
LH404_RS09725 1982909..1983100 - 192 WP_002911395.1 YebW family protein -
LH404_RS09730 1983198..1983437 - 240 WP_002911393.1 YebV family protein -
LH404_RS09735 1983553..1984986 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T220201 NZ_CP084986:1980409-1980511 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT220201 NZ_CP084986:c1980518-1980373 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References