Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 51221..52944 Replicon plasmid pDSM110277_d
Accession NZ_CP084963
Organism Sulfitobacter pontiacus strain DSM 110277

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag DSM110277_RS18130 Protein ID WP_092838803.1
Coordinates 51221..51862 (+) Length 214 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag DSM110277_RS18135 Protein ID WP_132998414.1
Coordinates 51862..52944 (+) Length 361 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSM110277_RS18120 (DSM110277_03642) 46637..48970 + 2334 WP_243252188.1 relaxase/mobilization nuclease domain-containing protein -
DSM110277_RS18125 (DSM110277_03643) 48979..50958 + 1980 WP_243252190.1 type IV secretory system conjugative DNA transfer family protein -
DSM110277_RS18130 (DSM110277_03644) 51221..51862 + 642 WP_092838803.1 DUF4433 domain-containing protein Toxin
DSM110277_RS18135 (DSM110277_03645) 51862..52944 + 1083 WP_132998414.1 macro domain-containing protein Antitoxin
DSM110277_RS18140 (DSM110277_03646) 53722..56367 + 2646 WP_243252195.1 hypothetical protein -
DSM110277_RS18145 (DSM110277_03647) 56586..57662 - 1077 WP_243252196.1 type IV secretion system protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..128813 128813


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(13-213)

Antitoxin

(18-130)


Sequences


Toxin        


Download         Length: 214 a.a.        Molecular weight: 24390.82 Da        Isoelectric Point: 7.1173

>T220174 WP_092838803.1 NZ_CP084963:51221-51862 [Sulfitobacter pontiacus]
MANNLTAEKALIFRITHINNVPWILRHGLHCKNSGVQDPNFVRIGNLELIQRRTARNVPVAPGGSLSDYIPFYFTPFSMM
MYNIKTGYGGIRQFPNTEIVIMASSLRGLEDRGVATVFSDRHAYLQTAQFFTSLDDLDKVDWGILQRRDFKRDVDDPEKT
DRYQAEALVHRHLPVEHLAGIVCLSENEKGTLEQQREEVGLDLKIVARPGWYF

Download         Length: 642 bp

>T220174 NZ_CP116976:208737-209111 [Escherichia coli]
ATGAACACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCTCATCTCCCGTAACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTCACGCTAAATGACACACCGTTCTCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCACCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 361 a.a.        Molecular weight: 40401.43 Da        Isoelectric Point: 5.9014

>AT220174 WP_132998414.1 NZ_CP084963:51862-52944 [Sulfitobacter pontiacus]
MVTYTQGNLLEADVDAVVNTVNTVGIMGKGIALMFKEQFPRNFEAYARACDEGEVRTGKMFVTENKELFGPRWIINFPTK
THWRVKTKIEWVEDGLKDLVRVIREKGINSIAIPPLGCGNGGLDWRDVRPLIESALAELEGVNAIVYEPTSKYQNVAKRT
GVEKLTPARALVAEMVRRYSLLGIECSILEVQKLGWFLERGVKRFGGSDALKFRFQANKYGPYSHNLTKLLDSLDGSYLR
CDKRLADADPLDLIWFNDAKYDRVQAYLNSGEGKQFSSVLEWASATIDGFESPLGMELLATVDWMMQHDDIEPTVEGVME
GLKDWAGGEVAGQRKLKIFDRRLVAIALGQLQISNRLPAC

Download         Length: 1083 bp

>AT220174 NZ_CP116976:208279-208647 [Escherichia coli]
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTCGGCGCTCGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAAAGGGCTGACCTGCAAAGCCGACACCCTCGGTAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCAACATCCGAAACGAAAAAGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References