Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 51221..52944 | Replicon | plasmid pDSM110277_d |
Accession | NZ_CP084963 | ||
Organism | Sulfitobacter pontiacus strain DSM 110277 |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | DSM110277_RS18130 | Protein ID | WP_092838803.1 |
Coordinates | 51221..51862 (+) | Length | 214 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | DSM110277_RS18135 | Protein ID | WP_132998414.1 |
Coordinates | 51862..52944 (+) | Length | 361 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DSM110277_RS18120 (DSM110277_03642) | 46637..48970 | + | 2334 | WP_243252188.1 | relaxase/mobilization nuclease domain-containing protein | - |
DSM110277_RS18125 (DSM110277_03643) | 48979..50958 | + | 1980 | WP_243252190.1 | type IV secretory system conjugative DNA transfer family protein | - |
DSM110277_RS18130 (DSM110277_03644) | 51221..51862 | + | 642 | WP_092838803.1 | DUF4433 domain-containing protein | Toxin |
DSM110277_RS18135 (DSM110277_03645) | 51862..52944 | + | 1083 | WP_132998414.1 | macro domain-containing protein | Antitoxin |
DSM110277_RS18140 (DSM110277_03646) | 53722..56367 | + | 2646 | WP_243252195.1 | hypothetical protein | - |
DSM110277_RS18145 (DSM110277_03647) | 56586..57662 | - | 1077 | WP_243252196.1 | type IV secretion system protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..128813 | 128813 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 214 a.a. Molecular weight: 24390.82 Da Isoelectric Point: 7.1173
>T220174 WP_092838803.1 NZ_CP084963:51221-51862 [Sulfitobacter pontiacus]
MANNLTAEKALIFRITHINNVPWILRHGLHCKNSGVQDPNFVRIGNLELIQRRTARNVPVAPGGSLSDYIPFYFTPFSMM
MYNIKTGYGGIRQFPNTEIVIMASSLRGLEDRGVATVFSDRHAYLQTAQFFTSLDDLDKVDWGILQRRDFKRDVDDPEKT
DRYQAEALVHRHLPVEHLAGIVCLSENEKGTLEQQREEVGLDLKIVARPGWYF
MANNLTAEKALIFRITHINNVPWILRHGLHCKNSGVQDPNFVRIGNLELIQRRTARNVPVAPGGSLSDYIPFYFTPFSMM
MYNIKTGYGGIRQFPNTEIVIMASSLRGLEDRGVATVFSDRHAYLQTAQFFTSLDDLDKVDWGILQRRDFKRDVDDPEKT
DRYQAEALVHRHLPVEHLAGIVCLSENEKGTLEQQREEVGLDLKIVARPGWYF
Download Length: 642 bp
>T220174 NZ_CP116976:208737-209111 [Escherichia coli]
ATGAACACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCTCATCTCCCGTAACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTCACGCTAAATGACACACCGTTCTCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCACCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGGCGAAATGA
ATGAACACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCTCATCTCCCGTAACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTCACGCTAAATGACACACCGTTCTCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCACCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGGCGAAATGA
Antitoxin
Download Length: 361 a.a. Molecular weight: 40401.43 Da Isoelectric Point: 5.9014
>AT220174 WP_132998414.1 NZ_CP084963:51862-52944 [Sulfitobacter pontiacus]
MVTYTQGNLLEADVDAVVNTVNTVGIMGKGIALMFKEQFPRNFEAYARACDEGEVRTGKMFVTENKELFGPRWIINFPTK
THWRVKTKIEWVEDGLKDLVRVIREKGINSIAIPPLGCGNGGLDWRDVRPLIESALAELEGVNAIVYEPTSKYQNVAKRT
GVEKLTPARALVAEMVRRYSLLGIECSILEVQKLGWFLERGVKRFGGSDALKFRFQANKYGPYSHNLTKLLDSLDGSYLR
CDKRLADADPLDLIWFNDAKYDRVQAYLNSGEGKQFSSVLEWASATIDGFESPLGMELLATVDWMMQHDDIEPTVEGVME
GLKDWAGGEVAGQRKLKIFDRRLVAIALGQLQISNRLPAC
MVTYTQGNLLEADVDAVVNTVNTVGIMGKGIALMFKEQFPRNFEAYARACDEGEVRTGKMFVTENKELFGPRWIINFPTK
THWRVKTKIEWVEDGLKDLVRVIREKGINSIAIPPLGCGNGGLDWRDVRPLIESALAELEGVNAIVYEPTSKYQNVAKRT
GVEKLTPARALVAEMVRRYSLLGIECSILEVQKLGWFLERGVKRFGGSDALKFRFQANKYGPYSHNLTKLLDSLDGSYLR
CDKRLADADPLDLIWFNDAKYDRVQAYLNSGEGKQFSSVLEWASATIDGFESPLGMELLATVDWMMQHDDIEPTVEGVME
GLKDWAGGEVAGQRKLKIFDRRLVAIALGQLQISNRLPAC
Download Length: 1083 bp
>AT220174 NZ_CP116976:208279-208647 [Escherichia coli]
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTCGGCGCTCGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAAAGGGCTGACCTGCAAAGCCGACACCCTCGGTAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCAACATCCGAAACGAAAAAGTAA
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTCGGCGCTCGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAAAGGGCTGACCTGCAAAGCCGACACCCTCGGTAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCAACATCCGAAACGAAAAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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