Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1839741..1840235 Replicon chromosome
Accession NZ_CP084916
Organism Carnobacterium viridans strain AB01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LHA31_RS09150 Protein ID WP_089976485.1
Coordinates 1839963..1840235 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1H0Z9X1
Locus tag LHA31_RS09145 Protein ID WP_035020339.1
Coordinates 1839741..1839962 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHA31_RS09130 (LHA31_09130) 1835273..1836142 + 870 WP_089976499.1 manganese catalase family protein -
LHA31_RS09135 (LHA31_09135) 1838036..1838449 + 414 WP_089976489.1 hypothetical protein -
LHA31_RS09140 (LHA31_09140) 1838742..1839203 + 462 WP_089976487.1 GNAT family N-acetyltransferase -
LHA31_RS09145 (LHA31_09145) 1839741..1839962 + 222 WP_035020339.1 DUF6290 family protein Antitoxin
LHA31_RS09150 (LHA31_09150) 1839963..1840235 + 273 WP_089976485.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LHA31_RS09155 (LHA31_09155) 1840745..1840960 + 216 WP_035020336.1 hypothetical protein -
LHA31_RS09160 (LHA31_09160) 1841066..1841788 - 723 WP_089976481.1 MerR family transcriptional regulator -
LHA31_RS09165 (LHA31_09165) 1841792..1842601 - 810 WP_035020334.1 Hsp33 family molecular chaperone HslO -
LHA31_RS09170 (LHA31_09170) 1843015..1843413 - 399 WP_035020332.1 hypothetical protein -
LHA31_RS09175 (LHA31_09175) 1843430..1843867 - 438 WP_035020331.1 LytTR family DNA-binding domain-containing protein -
LHA31_RS09180 (LHA31_09180) 1844770..1845036 - 267 WP_035020327.1 Txe/YoeB family addiction module toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-89)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10392.03 Da        Isoelectric Point: 10.3180

>T220153 WP_089976485.1 NZ_CP084916:1839963-1840235 [Carnobacterium viridans]
INSGYQVAFEKGAQKALKKMDKHQSLLIMGWIQKNLVNCTDPRKQGKGLTANRSGEWRYRIGDYRLIADISDERVPILML
EIGHRKDSYK

Download         Length: 273 bp

>T220153 NZ_CP116970:976323-976430 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8425.50 Da        Isoelectric Point: 4.3757

>AT220153 WP_035020339.1 NZ_CP084916:1839741-1839962 [Carnobacterium viridans]
MTVVSLRIDDHEDKLIKEYAKANNISVSTLFRNAVLEKIEDEIDLGLYNQAMSEHKENPRSISFEDMLKELAD

Download         Length: 222 bp

>AT220153 NZ_CP116970:c976273-976210 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1H0Z9X1

References