220152

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ImmA-IrrE/ImmA-HTH_26
Location 546626..547301 Replicon chromosome
Accession NZ_CP084916
Organism Carnobacterium viridans strain AB01

Toxin (Protein)


Gene name IrrE Uniprot ID -
Locus tag LHA31_RS02745 Protein ID WP_089978511.1
Coordinates 546957..547301 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ImmA Uniprot ID -
Locus tag LHA31_RS02740 Protein ID WP_089978513.1
Coordinates 546626..546946 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHA31_RS02685 (LHA31_02685) 542579..542782 - 204 WP_089978530.1 hypothetical protein -
LHA31_RS02690 (LHA31_02690) 542796..543296 - 501 WP_089978529.1 hypothetical protein -
LHA31_RS02695 (LHA31_02695) 543317..543994 - 678 WP_226776753.1 AAA family ATPase -
LHA31_RS02700 (LHA31_02700) 544019..544495 - 477 WP_089978525.1 siphovirus Gp157 family protein -
LHA31_RS02705 (LHA31_02705) 544495..544695 - 201 WP_089978522.1 hypothetical protein -
LHA31_RS02710 (LHA31_02710) 544771..545025 - 255 WP_089978521.1 hypothetical protein -
LHA31_RS02715 (LHA31_02715) 545022..545258 - 237 WP_089978519.1 hypothetical protein -
LHA31_RS02720 (LHA31_02720) 545408..545584 - 177 WP_176944134.1 hypothetical protein -
LHA31_RS02725 (LHA31_02725) 545599..545817 - 219 WP_089978517.1 hypothetical protein -
LHA31_RS02730 (LHA31_02730) 545990..546145 - 156 WP_176944133.1 hypothetical protein -
LHA31_RS02735 (LHA31_02735) 546160..546351 - 192 WP_089978514.1 hypothetical protein -
LHA31_RS02740 (LHA31_02740) 546626..546946 + 321 WP_089978513.1 helix-turn-helix transcriptional regulator Antitoxin
LHA31_RS02745 (LHA31_02745) 546957..547301 + 345 WP_089978511.1 ImmA/IrrE family metallo-endopeptidase Toxin
LHA31_RS02750 (LHA31_02750) 547365..547568 + 204 WP_089978510.1 hypothetical protein -
LHA31_RS02755 (LHA31_02755) 547638..548270 + 633 WP_089978508.1 DUF4352 domain-containing protein -
LHA31_RS02760 (LHA31_02760) 548402..549403 + 1002 Protein_535 recombinase family protein -
LHA31_RS02765 (LHA31_02765) 549631..550275 - 645 WP_226776678.1 JAB domain-containing protein -
LHA31_RS02770 (LHA31_02770) 550339..550998 - 660 WP_035022262.1 HAD family phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 506703..549790 43087


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

IrrE N-terminal-like domain

(28-89)

Antitoxin

Cro/C1-type helix-turn-helix domain

(5-59)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13263.15 Da        Isoelectric Point: 4.6009

>T220152 WP_089978511.1 NZ_CP084916:546957-547301 [Carnobacterium viridans]
MDSVFDLLELNNIELVLISIESNGYYDPALNIIFINQLLDEEKQKEVILHELGHVLNHKDLASLYSNKSYRSKMENEATK
FMIKYLINECEGQFNYSSVLEKYNLGIGWEGKIK

Download         Length: 345 bp

>T220152 NZ_CP116970:975788-975895 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12127.73 Da        Isoelectric Point: 5.2220

>AT220152 WP_089978513.1 NZ_CP084916:546626-546946 [Carnobacterium viridans]
MGIVDRIKILCDSHKTTFAEVERHVGLSNGQIRRWDTASPKLENIEKVADYFDVSVDYLRGKDTKVTLPTDLDKVLDGMM
SFDGKPMTENDRESIRAYLEGRFSDK

Download         Length: 321 bp

>AT220152 NZ_CP116970:c975735-975674 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References