Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 2225555..2226120 | Replicon | chromosome |
| Accession | NZ_CP084910 | ||
| Organism | Asticcacaulis sp. AND118 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LH365_RS10715 | Protein ID | WP_226743624.1 |
| Coordinates | 2225555..2225833 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | LH365_RS10720 | Protein ID | WP_226743625.1 |
| Coordinates | 2225830..2226120 (-) | Length | 97 a.a. |
Genomic Context
Location: 2222834..2223640 (807 bp)
Type: Others
Protein ID: WP_226743621.1
Type: Others
Protein ID: WP_226743621.1
Location: 2223823..2224341 (519 bp)
Type: Others
Protein ID: WP_226743622.1
Type: Others
Protein ID: WP_226743622.1
Location: 2227352..2228224 (873 bp)
Type: Others
Protein ID: WP_226743627.1
Type: Others
Protein ID: WP_226743627.1
Location: 2228469..2229620 (1152 bp)
Type: Others
Protein ID: WP_226743628.1
Type: Others
Protein ID: WP_226743628.1
Location: 2221101..2221514 (414 bp)
Type: Others
Protein ID: WP_255606586.1
Type: Others
Protein ID: WP_255606586.1
Location: 2221511..2221756 (246 bp)
Type: Others
Protein ID: WP_226743619.1
Type: Others
Protein ID: WP_226743619.1
Location: 2221777..2222775 (999 bp)
Type: Others
Protein ID: WP_226743620.1
Type: Others
Protein ID: WP_226743620.1
Location: 2224393..2225484 (1092 bp)
Type: Others
Protein ID: WP_226743623.1
Type: Others
Protein ID: WP_226743623.1
Location: 2225555..2225833 (279 bp)
Type: Toxin
Protein ID: WP_226743624.1
Type: Toxin
Protein ID: WP_226743624.1
Location: 2225830..2226120 (291 bp)
Type: Antitoxin
Protein ID: WP_226743625.1
Type: Antitoxin
Protein ID: WP_226743625.1
Location: 2226180..2227280 (1101 bp)
Type: Others
Protein ID: WP_226743626.1
Type: Others
Protein ID: WP_226743626.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LH365_RS10685 (LH365_10685) | 2221101..2221514 | - | 414 | WP_255606586.1 | YiiX/YebB-like N1pC/P60 family cysteine hydrolase | - |
| LH365_RS10690 (LH365_10690) | 2221511..2221756 | - | 246 | WP_226743619.1 | hypothetical protein | - |
| LH365_RS10695 (LH365_10695) | 2221777..2222775 | - | 999 | WP_226743620.1 | ketol-acid reductoisomerase | - |
| LH365_RS10700 (LH365_10700) | 2222834..2223640 | + | 807 | WP_226743621.1 | thymidylate synthase | - |
| LH365_RS10705 (LH365_10705) | 2223823..2224341 | + | 519 | WP_226743622.1 | dihydrofolate reductase | - |
| LH365_RS10710 (LH365_10710) | 2224393..2225484 | - | 1092 | WP_226743623.1 | NADH:flavin oxidoreductase | - |
| LH365_RS10715 (LH365_10715) | 2225555..2225833 | - | 279 | WP_226743624.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LH365_RS10720 (LH365_10720) | 2225830..2226120 | - | 291 | WP_226743625.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LH365_RS10725 (LH365_10725) | 2226180..2227280 | - | 1101 | WP_226743626.1 | Mrp/NBP35 family ATP-binding protein | - |
| LH365_RS10730 (LH365_10730) | 2227352..2228224 | + | 873 | WP_226743627.1 | tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA | - |
| LH365_RS10735 (LH365_10735) | 2228469..2229620 | + | 1152 | WP_226743628.1 | aldose epimerase family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10548.05 Da Isoelectric Point: 5.6643
>T220148 WP_226743624.1 NZ_CP084910:c2225833-2225555 [Asticcacaulis sp. AND118]
MMIQWSARALNDRIQTFQFIAQDSVAAAVRVDEAVEAAAEHLIDFPDSGRPGRARRTREWVLNGLPYLLIYTVEGDAIVI
WRVLHTSRLWPE
MMIQWSARALNDRIQTFQFIAQDSVAAAVRVDEAVEAAAEHLIDFPDSGRPGRARRTREWVLNGLPYLLIYTVEGDAIVI
WRVLHTSRLWPE
Download Length: 279 bp
>T220148 NZ_CP116970:323476-323579 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 97 a.a. Molecular weight: 10424.02 Da Isoelectric Point: 8.6819
>AT220148 WP_226743625.1 NZ_CP084910:c2226120-2225830 [Asticcacaulis sp. AND118]
MAASEVVQARIDRAIKERAGAVLSQMGLTVSDAVRILLTRIANEGTLPAGLTVDPETYDAWLRAKVQEAMNDPRPLVSHD
EAKARMAALRADALRK
MAASEVVQARIDRAIKERAGAVLSQMGLTVSDAVRILLTRIANEGTLPAGLTVDPETYDAWLRAKVQEAMNDPRPLVSHD
EAKARMAALRADALRK
Download Length: 291 bp
>AT220148 NZ_CP116970:c323617-323346 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT