Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) brnT-shpB/BrnT-BrnA
Location 402305..402899 Replicon chromosome
Accession NZ_CP084910
Organism Asticcacaulis sp. AND118

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag LH365_RS01900 Protein ID WP_226744532.1
Coordinates 402305..402601 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LH365_RS01905 Protein ID WP_226744533.1
Coordinates 402582..402899 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH365_RS01875 (LH365_01875) 397540..397749 + 210 WP_226744527.1 hypothetical protein -
LH365_RS01880 (LH365_01880) 398021..398233 + 213 WP_226744528.1 zinc-finger domain-containing protein -
LH365_RS01885 (LH365_01885) 398233..398700 + 468 WP_226744529.1 VOC family protein -
LH365_RS01890 (LH365_01890) 398900..399268 + 369 WP_226744530.1 DUF559 domain-containing protein -
LH365_RS01895 (LH365_01895) 399406..402267 + 2862 WP_226744531.1 DNA polymerase I -
LH365_RS01900 (LH365_01900) 402305..402601 + 297 WP_226744532.1 BrnT family toxin Toxin
LH365_RS01905 (LH365_01905) 402582..402899 + 318 WP_226744533.1 BrnA antitoxin family protein Antitoxin
LH365_RS01910 (LH365_01910) 402904..403338 + 435 WP_226744534.1 zinc ribbon domain-containing protein -
LH365_RS01915 (LH365_01915) 403335..403733 + 399 WP_226744535.1 VOC family protein -
LH365_RS01920 (LH365_01920) 403878..405560 + 1683 WP_226744536.1 methyl-accepting chemotaxis protein -
LH365_RS01925 (LH365_01925) 405616..407325 - 1710 WP_226744537.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(8-89)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-97)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11524.91 Da        Isoelectric Point: 4.5642

>T220146 WP_226744532.1 NZ_CP084910:402305-402601 [Asticcacaulis sp. AND118]
MTDTLFEWDDVKALSNLRKHGVDFDTATLVFYDPFAVTEMDRIEGGEQRWQTLGRVNDTLLLLVAHTVWDDDDTEIIRII
SARQAVPKERRKYEQQNR

Download         Length: 297 bp

>T220146 NZ_CP116964:51787-51897 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11957.80 Da        Isoelectric Point: 10.4623

>AT220146 WP_226744533.1 NZ_CP084910:402582-402899 [Asticcacaulis sp. AND118]
MSSKIVRRIFDPANPPVLTEAQKRQLEALAARPDSEIDVSDIPPLTDGFWENALRNPFMRPVKQQATVRLDADVLDWLKS
SGKGYQTRLNAILRKEMLADLKRRA

Download         Length: 318 bp

>AT220146 NZ_CP116964:c52002-51938 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References