Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012672..2012943 Replicon chromosome
Accession NZ_CP084900
Organism Escherichia coli strain EC20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012802..2012905 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012672..2012943 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHL15_RS09695 2009227..2009889 - 663 WP_000944256.1 exodeoxyribonuclease X -
LHL15_RS09700 2009913..2010569 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
LHL15_RS09705 2010671..2010901 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LHL15_RS09710 2011040..2011414 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LHL15_RS09715 2011418..2012290 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
LHL15_RS09720 2012303..2012644 + 342 WP_000976472.1 YebY family protein -
- 2012672..2012943 - 272 - - Antitoxin
- 2012802..2012905 + 104 - - Toxin
LHL15_RS09725 2013040..2013696 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
LHL15_RS09730 2013697..2013888 - 192 WP_001296140.1 YebW family protein -
LHL15_RS09735 2013993..2014229 - 237 WP_001295499.1 YebV family protein -
LHL15_RS09740 2014347..2015786 - 1440 WP_061344305.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T220119 NZ_CP084900:2012802-2012905 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT220119 NZ_CP084900:c2012943-2012672 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References