Detailed information of TA system TA219794

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 4316062..4316423
• Replicon: chromosome
• Accession: NZ_CP084891
• Organism: Xanthomonas citri pv. mangiferaeindicae strain GZ09

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: -
• Locus tag: LCZ91_RS18775
• Protein ID: WP_033482596.1
• Coordinates: 4316062..4316196 (-)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: H8FG64
• Locus tag: LCZ91_RS18780
• Protein ID: WP_003486606.1
• Coordinates: 4316271..4316423 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LCZ91_RS18755 (LCZ91_18755)	4311199..4312890	-	1692	WP_033482594.1	M28 family metallopeptidase	-
LCZ91_RS18760 (LCZ91_18760)	4313082..4314026	-	945	WP_003486596.1	MBL fold metallo-hydrolase	-
LCZ91_RS18765 (LCZ91_18765)	4314155..4315444	-	1290	WP_003486598.1	tryptophan--tRNA ligase	-
LCZ91_RS18770 (LCZ91_18770)	4315626..4315835	-	210	WP_003486601.1	CsbD family protein	-
LCZ91_RS18775 (LCZ91_18775)	4316062..4316196	-	135	WP_033482596.1	entericidin A/B family lipoprotein	Toxin
LCZ91_RS18780 (LCZ91_18780)	4316271..4316423	-	153	WP_003486606.1	entericidin A/B family lipoprotein	Antitoxin
LCZ91_RS18785 (LCZ91_18785)	4316530..4317453	-	924	WP_003486608.1	arginase	-
LCZ91_RS18790 (LCZ91_18790)	4317774..4318226	+	453	WP_003486611.1	roadblock/LC7 domain-containing protein	-
LCZ91_RS18795 (LCZ91_18795)	4318290..4318676	+	387	WP_226689943.1	roadblock/LC7 domain-containing protein	-
LCZ91_RS18800 (LCZ91_18800)	4318773..4319690	+	918	WP_226689944.1	hypothetical protein	-
LCZ91_RS18805 (LCZ91_18805)	4319687..4320229	+	543	WP_003486615.1	GTPase	-
LCZ91_RS18810 (LCZ91_18810)	4320667..4321350	+	684	WP_003486617.1	dTMP kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4503.38 Da
• Isoelectric Point: 9.3487

>T219794 WP_033482596.1 NZ_CP084891:c4316196-4316062 [Xanthomonas citri pv. mangiferaeindicae]
MKRTIVLLVLSMLSVAMLAGCNTVAGAGKDVQGAGEKVEDAARK

Nucleotide

• Length: 135 bp

>T219794 NZ_CP116717:2731645-2732220 [Pseudomonas aeruginosa]
ATGAGGCATTCCCCATTCACCGCCGTCTACGACGCGTGCGTTCTATATCCCGCGCCACTGCGGGATTTCCTGATGTGGCT
CGGCCTGTCTGGCCGCTTCCGGGCGCGGTGGAGCCAAGCCATTCATGAGGAGTGGAAACGCAACCTGTTGATCAACCGCC
CCGATCTCACCCGGGTTCAGGTCGACAGGACGTCGGATCTCATGGACAGGGCCATTCCGGACGGCTTGGTGGAGGGCTAC
GAAGCGCTCGTGGCAGGCCTGACATTACCCGATCCGAATGATCGGCACGTCCTGGCTGCGGCGATTCGCTGCGGTGCGAG
CGTGATTGTGACGTTCAACGAACGTGATTTCCCGAACGATCTGCTGGCTCCGTACGGCATCGAATCGCAGCACCCCGATG
AGTTTGTGGACAACCTGCTGGATCTGGATGCGGCCGCCGTAGTGTCGGCTGCGCAGCGCCAGCGTGCCCAACTCAAGCAT
CCGCCGATCGATGTGGACCGCTATCTCGAAATCCTGCTGCGCCAAGGCCTTGTGCAAACGACCAAGGTGCTGGCGACCTA
TCGCACCATTCTCTGA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5122.07 Da
• Isoelectric Point: 8.7942

>AT219794 WP_003486606.1 NZ_CP084891:c4316423-4316271 [Xanthomonas citri pv. mangiferaeindicae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Nucleotide

• Length: 153 bp

>AT219794 NZ_CP116717:2731178-2731648 [Pseudomonas aeruginosa]
ATGACCACCGCCACTGCCCAATCCAAGATGACCCTTCCCGCCGCGGGAGAGGTTAAGGCAGCCGTCCAGGGTCAACGTGC
CTTGGCGGCTTACCTCGCAACCCAGTTCGAGACGCAGCACATCCAGATCTTTGATGACCACAAACAGGCTCATCAGGTGG
AACTGCCTACCTCGGCTTTACGCCTGCTGGTCGACATCCTGGCCGAGTTGGCCGATGGCAATGCAGTAAAGGTGGTGCCC
GTCCATGCAGAGCTGACGACCCAAGAGGCGGCGGACTTGCTCAACGTGTCCCGTCCCCATTTCGTCAAGCTGCTAGAAGA
TGGGGTGTTGGCATTTCATCGCACCGGCAAGCACCGCAGGGTGAGGTTCGCCGATCTGATGCAGTACAAGGAAGCGCGCG
AGCGCGCCAGTGAGCAGGCGATGGCCGAACTCGCTCAGCAGTCGCAAGAGTTGGGAATGGGATACGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A828YLX6