Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2555562..2555796 | Replicon | chromosome |
| Accession | NZ_CP084879 | ||
| Organism | Shigella flexneri strain CMCC51574 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2555563..2555666 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2555562..2555796 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LGV73_RS13100 | 2551097..2551369 | + | 273 | WP_001277358.1 | host-nuclease inhibitor Gam family protein | - |
| LGV73_RS13105 | 2551399..2552496 | + | 1098 | WP_001173296.1 | AAA family ATPase | - |
| LGV73_RS13110 | 2552547..2552735 | + | 189 | WP_000276807.1 | DUF1187 family protein | - |
| - | 2552553..2552731 | - | 179 | NuclAT_0 | - | - |
| - | 2552553..2552731 | - | 179 | NuclAT_0 | - | - |
| - | 2552553..2552731 | - | 179 | NuclAT_0 | - | - |
| - | 2552553..2552731 | - | 179 | NuclAT_0 | - | - |
| LGV73_RS13115 | 2552836..2553991 | + | 1156 | WP_134796927.1 | IS3-like element IS600 family transposase | - |
| LGV73_RS13120 | 2554108..2554389 | + | 282 | WP_005127484.1 | excisionase | - |
| LGV73_RS13125 | 2554355..2555431 | + | 1077 | Protein_2568 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2555562..2555796 | + | 235 | - | - | Antitoxin |
| - | 2555563..2555666 | - | 104 | - | - | Toxin |
| LGV73_RS13130 | 2555824..2556165 | - | 342 | WP_000976476.1 | YebY family protein | - |
| LGV73_RS13135 | 2556178..2557050 | - | 873 | Protein_2570 | copper homeostasis membrane protein CopD | - |
| LGV73_RS13140 | 2557054..2557428 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| LGV73_RS13145 | 2557567..2557797 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| LGV73_RS13150 | 2557899..2558555 | + | 657 | Protein_2573 | carbon-nitrogen hydrolase family protein YobB | - |
| LGV73_RS13155 | 2558579..2559241 | + | 663 | WP_000944270.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T219782 NZ_CP084879:c2555666-2555563 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT219782 NZ_CP084879:2555562-2555796 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
