Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1885056..1885196 Replicon chromosome
Accession NZ_CP084874
Organism Klebsiella africana strain 200023

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1885092..1885194 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1885056..1885196 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL98_RS09095 (LGL98_09095) 1880187..1882247 + 2061 WP_136030185.1 oligopeptidase B -
LGL98_RS09100 (LGL98_09100) 1882251..1882910 - 660 WP_136030187.1 exodeoxyribonuclease X -
LGL98_RS09105 (LGL98_09105) 1882989..1883219 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LGL98_RS09110 (LGL98_09110) 1883333..1883707 + 375 WP_136030189.1 CopC domain-containing protein YobA -
LGL98_RS09115 (LGL98_09115) 1883709..1884578 + 870 WP_136030191.1 copper homeostasis membrane protein CopD -
LGL98_RS09120 (LGL98_09120) 1884595..1884933 + 339 WP_168435238.1 YebY family protein -
- 1885056..1885196 - 141 - - Antitoxin
- 1885092..1885194 + 103 - - Toxin
LGL98_RS09125 (LGL98_09125) 1885563..1886525 - 963 WP_136030193.1 glycosyltransferase family 2 protein -
LGL98_RS09130 (LGL98_09130) 1886800..1887933 - 1134 Protein_1778 IS3 family transposase -
LGL98_RS09135 (LGL98_09135) 1888153..1888296 - 144 WP_168435244.1 Ecr family regulatory small membrane protein -
LGL98_RS09140 (LGL98_09140) 1888401..1889369 - 969 WP_168435239.1 VirK/YbjX family protein -
LGL98_RS09145 (LGL98_09145) 1889526..1890179 + 654 WP_136030196.1 protein-serine/threonine phosphatase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1866318..1900859 34541


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219732 NZ_CP084874:1885092-1885194 [Klebsiella africana]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT219732 NZ_CP084874:c1885196-1885056 [Klebsiella africana]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References