Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013049..2013194 Replicon chromosome
Accession NZ_CP084871
Organism Klebsiella pneumoniae strain 04A025

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013085..2013187 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013049..2013194 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM00_RS09860 2008179..2010239 + 2061 WP_004151449.1 oligopeptidase B -
LGM00_RS09865 2010243..2010902 - 660 WP_020324964.1 exodeoxyribonuclease X -
LGM00_RS09870 2010981..2011211 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM00_RS09875 2011324..2011698 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LGM00_RS09880 2011702..2012571 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
LGM00_RS09885 2012588..2012926 + 339 WP_002911404.1 YebY family protein -
- 2013049..2013194 - 146 - - Antitoxin
- 2013085..2013187 + 103 - - Toxin
LGM00_RS09890 2013563..2013706 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LGM00_RS09895 2013811..2014779 - 969 WP_004151446.1 VirK/YbjX family protein -
LGM00_RS09900 2014936..2015589 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LGM00_RS09905 2015586..2015777 - 192 WP_002911395.1 YebW family protein -
LGM00_RS09910 2015875..2016114 - 240 WP_002911393.1 YebV family protein -
LGM00_RS09915 2016230..2017663 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219694 NZ_CP084871:2013085-2013187 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219694 NZ_CP084871:c2013194-2013049 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References