Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3686830..3686975 Replicon chromosome
Accession NZ_CP084870
Organism Klebsiella pneumoniae strain BJ1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3686837..3686939 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3686830..3686975 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM01_RS17705 3682362..3683795 + 1434 WP_032446224.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LGM01_RS17710 3683911..3684150 + 240 WP_002911393.1 YebV family protein -
LGM01_RS17715 3684248..3684439 + 192 WP_002911395.1 YebW family protein -
LGM01_RS17720 3684436..3685089 - 654 WP_032446225.1 protein-serine/threonine phosphatase -
LGM01_RS17725 3685246..3686214 + 969 WP_004151446.1 VirK/YbjX family protein -
LGM01_RS17730 3686319..3686462 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3686830..3686975 + 146 - - Antitoxin
- 3686837..3686939 - 103 - - Toxin
LGM01_RS17735 3687098..3687436 - 339 WP_002911404.1 YebY family protein -
LGM01_RS17740 3687453..3688322 - 870 WP_032446226.1 copper homeostasis membrane protein CopD -
LGM01_RS17745 3688326..3688700 - 375 WP_004151448.1 CopC domain-containing protein YobA -
LGM01_RS17750 3688813..3689043 + 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM01_RS17755 3689122..3689781 + 660 WP_032446227.1 exodeoxyribonuclease X -
LGM01_RS17760 3689785..3691845 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219682 NZ_CP084870:c3686939-3686837 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219682 NZ_CP084870:3686830-3686975 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References