21961

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 67607..68955 Replicon plasmid pSbal02
Accession NC_009036
Organism Shewanella baltica OS155

Toxin (Protein)


Gene name sanaT Uniprot ID A3DB90
Locus tag SBAL_RS23550 Protein ID WP_011840016.1
Coordinates 68014..68955 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A3DB89
Locus tag SBAL_RS23545 Protein ID WP_006087348.1
Coordinates 67607..68017 (+) Length 137 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBAL_RS23525 64314..64565 + 252 Protein_71 transposase -
SBAL_RS24265 64501..64809 - 309 Protein_72 recombinase family protein -
SBAL_RS24740 65513..65836 + 324 WP_011840013.1 hypothetical protein -
SBAL_RS23535 65879..66514 + 636 WP_011840014.1 SDR family NAD(P)-dependent oxidoreductase -
SBAL_RS23540 66778..67389 + 612 WP_011840015.1 recombinase family protein -
SBAL_RS23545 67607..68017 + 411 WP_006087348.1 hypothetical protein Antitoxin
SBAL_RS23550 68014..68955 + 942 WP_011840016.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
SBAL_RS23555 68963..71554 + 2592 WP_011840017.1 type I restriction-modification system subunit M -
SBAL_RS24745 71556..71810 + 255 WP_086015433.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..74000 74000


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 314 a.a.        Molecular weight: 35814.71 Da        Isoelectric Point: 6.8358

>T21961 WP_011840016.1 NC_009036:68014-68955 [Shewanella baltica OS155]
MKKLKQQFLEVSDALALGNPAIIEKDYWVVALLSELEQLTFETHQMVFSGGTALAKSNVKILRMSEDVDIKLIPTPQFQH
LSRGRKKQYRKALAVQIETALIASNKFSIEARLVQDEYRYVEYELKYPQQFSQAPCLRPIIKLELMETIPLLALETRGIQ
SLVAELYKLPQEVNVFICVSVNTTLVEKVLSMLRRTMSVKRDAARNDDVTLVRHIYDVHCIHAAQALDNELLAPLFLAIL
AEDIARFGNQHAEFVMDPANELRLGLQEIESNPLFRQRFNDFVKPMVFNSQSPNFDTCFMSFKHIATSLILTI

Download         Length: 942 bp

>T21961 NC_009036:68014-68955 [Shewanella baltica OS155]
ATGAAAAAACTGAAACAACAGTTCTTAGAGGTTTCCGATGCATTAGCGCTCGGGAACCCCGCCATAATTGAAAAAGATTA
TTGGGTGGTTGCTCTACTTTCAGAGCTTGAACAGCTAACGTTTGAAACTCATCAAATGGTGTTTTCCGGCGGCACCGCAC
TTGCTAAGTCCAATGTCAAAATACTTCGAATGTCTGAAGACGTGGACATAAAGCTGATCCCCACGCCGCAATTTCAACAC
CTTAGTCGTGGCAGGAAAAAACAGTACCGTAAAGCATTAGCAGTACAAATTGAAACAGCGCTTATTGCATCTAACAAATT
TTCTATCGAAGCTAGATTAGTTCAGGATGAATATCGCTATGTGGAATATGAGCTTAAATATCCGCAACAATTTAGCCAGG
CTCCTTGTCTACGCCCAATCATCAAGTTAGAACTGATGGAAACCATTCCACTGCTTGCGCTGGAAACGCGGGGCATTCAA
TCGTTAGTCGCAGAGCTTTATAAGCTGCCACAAGAAGTGAACGTATTCATCTGCGTATCAGTAAATACCACCTTGGTAGA
GAAAGTGCTTTCCATGTTACGCCGCACAATGTCTGTTAAGCGTGATGCAGCCCGAAACGATGACGTCACCTTAGTTAGAC
ATATTTACGACGTACACTGTATTCATGCAGCACAGGCCCTTGATAATGAATTACTTGCGCCCCTTTTTCTCGCCATATTA
GCAGAAGATATTGCTCGCTTTGGCAACCAACATGCCGAATTCGTCATGGACCCAGCTAATGAGTTACGCCTTGGCTTACA
GGAGATAGAAAGCAACCCACTCTTCAGGCAACGCTTTAATGATTTTGTTAAACCCATGGTGTTTAACTCGCAATCACCCA
ATTTTGATACGTGCTTTATGTCCTTTAAACATATTGCGACCTCACTCATTCTGACTATTTAG

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 15505.88 Da        Isoelectric Point: 10.3652

>AT21961 WP_006087348.1 NC_009036:67607-68017 [Shewanella baltica OS155]
MAAVDSIFQKIKRSRRYVFERKDFDGIASYDQIGRSLNQLMDRGEIMKLGYGLYTKARVNSLTGRLMPTCPGGSDALMRE
ILKMKDIDFEIDNLSLQSLSGKNTQIPSSVHYSWDQKQFNRKLVVGNRLLTPASRP

Download         Length: 411 bp

>AT21961 NC_009036:67607-68017 [Shewanella baltica OS155]
ATGGCAGCTGTTGACAGTATCTTTCAAAAAATAAAGCGTTCTAGACGCTACGTTTTCGAACGCAAAGACTTTGACGGCAT
TGCTAGCTATGACCAGATTGGCAGATCGCTTAACCAGTTAATGGATAGAGGCGAGATAATGAAGCTTGGCTATGGCTTAT
ACACTAAAGCGCGAGTAAATAGCCTGACAGGACGTTTAATGCCGACCTGTCCAGGTGGTAGCGATGCACTTATGCGTGAA
ATATTGAAAATGAAAGACATCGATTTCGAGATAGATAATCTGTCCTTACAAAGTCTTTCCGGTAAAAACACCCAAATTCC
CTCATCAGTTCATTACTCATGGGATCAAAAACAGTTCAATCGAAAATTGGTTGTTGGTAACAGACTGTTGACGCCAGCAA
GTAGACCATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A3DB90


Antitoxin

Source ID Structure
AlphaFold DB A3DB89

References