Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1971167..1971312 Replicon chromosome
Accession NZ_CP084859
Organism Klebsiella pneumoniae strain SB1139

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1971203..1971305 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1971167..1971312 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM11_RS09585 1966297..1968357 + 2061 WP_004151449.1 oligopeptidase B -
LGM11_RS09590 1968361..1969020 - 660 WP_002911407.1 exodeoxyribonuclease X -
LGM11_RS09595 1969099..1969329 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM11_RS09600 1969442..1969816 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LGM11_RS09605 1969820..1970689 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LGM11_RS09610 1970706..1971044 + 339 WP_002911404.1 YebY family protein -
- 1971167..1971312 - 146 - - Antitoxin
- 1971203..1971305 + 103 - - Toxin
LGM11_RS09615 1971680..1971823 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LGM11_RS09620 1971928..1972896 - 969 WP_004151446.1 VirK/YbjX family protein -
LGM11_RS09625 1973053..1973706 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LGM11_RS09630 1973703..1973894 - 192 WP_002911395.1 YebW family protein -
LGM11_RS09635 1973992..1974231 - 240 WP_002911393.1 YebV family protein -
LGM11_RS09640 1974347..1975780 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219597 NZ_CP084859:1971203-1971305 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219597 NZ_CP084859:c1971312-1971167 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References