Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2032969..2033114 Replicon chromosome
Accession NZ_CP084852
Organism Klebsiella pneumoniae strain SB2390

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2033005..2033107 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2032969..2033114 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM13_RS10030 2028099..2030159 + 2061 WP_004151449.1 oligopeptidase B -
LGM13_RS10035 2030163..2030822 - 660 WP_004180433.1 exodeoxyribonuclease X -
LGM13_RS10040 2030901..2031131 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM13_RS10045 2031244..2031618 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LGM13_RS10050 2031622..2032491 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
LGM13_RS10055 2032508..2032846 + 339 WP_002911404.1 YebY family protein -
- 2032969..2033114 - 146 - - Antitoxin
- 2033005..2033107 + 103 - - Toxin
LGM13_RS10060 2033483..2033626 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LGM13_RS10065 2033731..2034699 - 969 WP_004151446.1 VirK/YbjX family protein -
LGM13_RS10070 2034856..2035509 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LGM13_RS10075 2035506..2035697 - 192 WP_002911395.1 YebW family protein -
LGM13_RS10080 2035795..2036034 - 240 WP_002911393.1 YebV family protein -
LGM13_RS10085 2036150..2037583 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219558 NZ_CP084852:2033005-2033107 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219558 NZ_CP084852:c2033114-2032969 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References