Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1998750..1998895 Replicon chromosome
Accession NZ_CP084843
Organism Klebsiella pneumoniae strain SB611

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1998786..1998888 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1998750..1998895 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM15_RS09900 1993880..1995940 + 2061 WP_004151449.1 oligopeptidase B -
LGM15_RS09905 1995944..1996603 - 660 WP_002911407.1 exodeoxyribonuclease X -
LGM15_RS09910 1996682..1996912 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM15_RS09915 1997025..1997399 + 375 WP_016529032.1 CopC domain-containing protein YobA -
LGM15_RS09920 1997403..1998272 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LGM15_RS09925 1998289..1998627 + 339 WP_002911404.1 YebY family protein -
- 1998750..1998895 - 146 - - Antitoxin
- 1998786..1998888 + 103 - - Toxin
LGM15_RS09930 1999263..1999406 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LGM15_RS09935 1999511..2000479 - 969 WP_074421963.1 VirK/YbjX family protein -
LGM15_RS09940 2000636..2001289 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
LGM15_RS09945 2001286..2001477 - 192 WP_002911395.1 YebW family protein -
LGM15_RS09950 2001575..2001814 - 240 WP_002911393.1 YebV family protein -
LGM15_RS09955 2001930..2003363 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219538 NZ_CP084843:1998786-1998888 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219538 NZ_CP084843:c1998895-1998750 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References