Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1934148..1934293 Replicon chromosome
Accession NZ_CP084830
Organism Klebsiella pneumoniae strain SB612

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1934184..1934286 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1934148..1934293 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM16_RS09480 (LGM16_09480) 1929278..1931338 + 2061 WP_004151449.1 oligopeptidase B -
LGM16_RS09485 (LGM16_09485) 1931342..1932001 - 660 WP_002911407.1 exodeoxyribonuclease X -
LGM16_RS09490 (LGM16_09490) 1932080..1932310 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM16_RS09495 (LGM16_09495) 1932423..1932797 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LGM16_RS09500 (LGM16_09500) 1932801..1933670 + 870 WP_023316211.1 copper homeostasis membrane protein CopD -
LGM16_RS09505 (LGM16_09505) 1933687..1934025 + 339 WP_002911404.1 YebY family protein -
- 1934148..1934293 - 146 - - Antitoxin
- 1934184..1934286 + 103 - - Toxin
LGM16_RS09510 (LGM16_09510) 1934661..1934804 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LGM16_RS09515 (LGM16_09515) 1934909..1935877 - 969 WP_004151446.1 VirK/YbjX family protein -
LGM16_RS09520 (LGM16_09520) 1936034..1936687 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
LGM16_RS09525 (LGM16_09525) 1936684..1936875 - 192 WP_002911395.1 YebW family protein -
LGM16_RS09530 (LGM16_09530) 1936973..1937212 - 240 WP_002911393.1 YebV family protein -
LGM16_RS09535 (LGM16_09535) 1937328..1938761 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219514 NZ_CP084830:1934184-1934286 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219514 NZ_CP084830:c1934293-1934148 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References