Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1838810..1838955 Replicon chromosome
Accession NZ_CP084829
Organism Klebsiella pneumoniae strain SB615

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1838846..1838948 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1838810..1838955 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM17_RS08875 1833940..1836000 + 2061 WP_004151449.1 oligopeptidase B -
LGM17_RS08880 1836004..1836663 - 660 WP_002911407.1 exodeoxyribonuclease X -
LGM17_RS08885 1836742..1836972 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM17_RS08890 1837085..1837459 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LGM17_RS08895 1837463..1838332 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
LGM17_RS08900 1838349..1838687 + 339 WP_016529031.1 YebY family protein -
- 1838810..1838955 - 146 - - Antitoxin
- 1838846..1838948 + 103 - - Toxin
LGM17_RS08905 1839323..1839466 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LGM17_RS08910 1839571..1840539 - 969 WP_004151446.1 VirK/YbjX family protein -
LGM17_RS08915 1840696..1841349 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
LGM17_RS08920 1841346..1841537 - 192 WP_002911395.1 YebW family protein -
LGM17_RS08925 1841635..1841874 - 240 WP_002911393.1 YebV family protein -
LGM17_RS08930 1841990..1843423 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219497 NZ_CP084829:1838846-1838948 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219497 NZ_CP084829:c1838955-1838810 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References