Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 2317614..2318582 | Replicon | chromosome |
| Accession | NC_008800 | ||
| Organism | Yersinia enterocolitica subsp. enterocolitica 8081 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | Q9F4G8 |
| Locus tag | YE_RS10590 | Protein ID | WP_005169553.1 |
| Coordinates | 2318124..2318582 (+) | Length | 153 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | Q9F4G7 |
| Locus tag | YE_RS10585 | Protein ID | WP_005169556.1 |
| Coordinates | 2317614..2318060 (+) | Length | 149 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| YE_RS10565 (YE2111) | 2313263..2313970 | + | 708 | WP_011816358.1 | murein tripeptide amidase MpaA | - |
| YE_RS10570 (YE2112) | 2313967..2314938 | - | 972 | WP_011816359.1 | L-Ala-D/L-Glu epimerase | - |
| YE_RS10575 (YE2113) | 2315091..2315594 | + | 504 | WP_011816360.1 | thiol peroxidase | - |
| YE_RS10580 (YE2114) | 2315717..2317294 | - | 1578 | WP_005169566.1 | transcriptional regulator TyrR | - |
| YE_RS10585 (YE2115) | 2317614..2318060 | + | 447 | WP_005169556.1 | DUF2384 domain-containing protein | Antitoxin |
| YE_RS10590 (YE2116) | 2318124..2318582 | + | 459 | WP_005169553.1 | RES family NAD+ phosphorylase | Toxin |
| YE_RS10595 (YE2117) | 2318585..2319649 | - | 1065 | WP_005169550.1 | YcjF family protein | - |
| YE_RS10600 (YE2118) | 2319646..2321043 | - | 1398 | WP_005169547.1 | YcjX family protein | - |
| YE_RS10605 (YE2118A) | 2321024..2321263 | - | 240 | WP_042661425.1 | phage shock protein PspD | - |
| YE_RS10610 (YE2119) | 2321309..2321728 | - | 420 | WP_162484193.1 | envelope stress response membrane protein PspC | - |
| YE_RS10615 (YE2120) | 2321728..2321955 | - | 228 | WP_005161022.1 | envelope stress response membrane protein PspB | - |
| YE_RS10620 (YE2121) | 2322117..2322782 | - | 666 | WP_005169534.1 | phage shock protein PspA | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 153 a.a. Molecular weight: 17222.60 Da Isoelectric Point: 4.8675
>T21943 WP_005169553.1 NC_008800:2318124-2318582 [Yersinia enterocolitica subsp. enterocolitica 8081]
MMLYRIVMRRYLASTWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHIQDSSTLSEFELFQIEIEDSNIMLLQPQ
DWPTNWRSDPAPATTMDIGTEWLESESSLGLLVPSTLVPTENNLLLNPRHKSFQTCLSSVQPLSFAFDPRLK
MMLYRIVMRRYLASTWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHIQDSSTLSEFELFQIEIEDSNIMLLQPQ
DWPTNWRSDPAPATTMDIGTEWLESESSLGLLVPSTLVPTENNLLLNPRHKSFQTCLSSVQPLSFAFDPRLK
Download Length: 459 bp
>T21943 NC_008800:2318124-2318582 [Yersinia enterocolitica subsp. enterocolitica 8081]
ATGATGCTCTACCGCATTGTGATGCGCCGCTATCTTGCCTCAACCTGGACCGGCTATGGTGCCGAAACCTATGGTGGCCG
CTGGAACCATAAGGGGCACGCCGCCATCTACTTAGCCAGCAGTGTATCACTGGCGATGTTGGAGACGTTGGTACATATTC
AGGACAGCTCAACACTGAGTGAGTTCGAGTTATTCCAAATTGAAATCGAAGATAGCAACATTATGCTGCTTCAGCCGCAA
GATTGGCCCACGAACTGGCGCAGCGACCCCGCACCTGCGACCACAATGGATATCGGCACTGAATGGCTGGAGTCAGAATC
ATCACTTGGATTACTGGTTCCATCCACTCTGGTGCCGACAGAAAACAATCTACTGCTCAATCCTCGGCACAAAAGCTTTC
AAACCTGCTTAAGCAGTGTTCAACCACTCTCTTTTGCCTTTGACCCACGGCTGAAATAG
ATGATGCTCTACCGCATTGTGATGCGCCGCTATCTTGCCTCAACCTGGACCGGCTATGGTGCCGAAACCTATGGTGGCCG
CTGGAACCATAAGGGGCACGCCGCCATCTACTTAGCCAGCAGTGTATCACTGGCGATGTTGGAGACGTTGGTACATATTC
AGGACAGCTCAACACTGAGTGAGTTCGAGTTATTCCAAATTGAAATCGAAGATAGCAACATTATGCTGCTTCAGCCGCAA
GATTGGCCCACGAACTGGCGCAGCGACCCCGCACCTGCGACCACAATGGATATCGGCACTGAATGGCTGGAGTCAGAATC
ATCACTTGGATTACTGGTTCCATCCACTCTGGTGCCGACAGAAAACAATCTACTGCTCAATCCTCGGCACAAAAGCTTTC
AAACCTGCTTAAGCAGTGTTCAACCACTCTCTTTTGCCTTTGACCCACGGCTGAAATAG
Antitoxin
Download Length: 149 a.a. Molecular weight: 16336.80 Da Isoelectric Point: 9.8753
>AT21943 WP_005169556.1 NC_008800:2317614-2318060 [Yersinia enterocolitica subsp. enterocolitica 8081]
MRAYHPTPATKTRALWREIGLPASRGTVLVDSIKMGFSVDVIDSIHLWASIPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKGKAITWMSTPIKGLGHRSPDSLLETETGALEVCDLIGRLEHGVFS
MRAYHPTPATKTRALWREIGLPASRGTVLVDSIKMGFSVDVIDSIHLWASIPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKGKAITWMSTPIKGLGHRSPDSLLETETGALEVCDLIGRLEHGVFS
Download Length: 447 bp
>AT21943 NC_008800:2317614-2318060 [Yersinia enterocolitica subsp. enterocolitica 8081]
ATGAGAGCGTATCACCCCACTCCAGCGACCAAAACAAGGGCGCTATGGCGAGAGATTGGTTTGCCCGCCAGCCGCGGTAC
GGTATTGGTCGATAGCATCAAAATGGGTTTTTCTGTTGATGTCATTGACAGCATCCATCTATGGGCATCTATCCCAAAAG
CTGAAATCTTGCGTGCGACCGGTATTCCCAGCCGCAGCTTGACTCGCAGACGCACCCATGATGGCCGTTTCACTCCCGAA
GAGAGTGAGCGCATTGCGCGTTTCGTTCGGGTTATGGACGCCGCAGTTGATCTATTTGGCGGAGATAAAGGCAAAGCTAT
CACTTGGATGTCGACCCCGATTAAAGGCCTGGGCCACCGTAGTCCAGATTCCTTGCTGGAGACCGAAACCGGTGCATTGG
AAGTCTGTGATTTGATTGGACGCCTGGAGCACGGCGTATTTTCATAA
ATGAGAGCGTATCACCCCACTCCAGCGACCAAAACAAGGGCGCTATGGCGAGAGATTGGTTTGCCCGCCAGCCGCGGTAC
GGTATTGGTCGATAGCATCAAAATGGGTTTTTCTGTTGATGTCATTGACAGCATCCATCTATGGGCATCTATCCCAAAAG
CTGAAATCTTGCGTGCGACCGGTATTCCCAGCCGCAGCTTGACTCGCAGACGCACCCATGATGGCCGTTTCACTCCCGAA
GAGAGTGAGCGCATTGCGCGTTTCGTTCGGGTTATGGACGCCGCAGTTGATCTATTTGGCGGAGATAAAGGCAAAGCTAT
CACTTGGATGTCGACCCCGATTAAAGGCCTGGGCCACCGTAGTCCAGATTCCTTGCTGGAGACCGAAACCGGTGCATTGG
AAGTCTGTGATTTGATTGGACGCCTGGAGCACGGCGTATTTTCATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A8B6KS49 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A8B6KRT3 |