Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 39725..40272 Replicon plasmid unnamed1
Accession NZ_CP084753
Organism UNVERIFIED_ORG: Kinneretia sp. XES5

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LHK14_RS20070 Protein ID WP_226922276.1
Coordinates 39725..40018 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LHK14_RS20075 Protein ID WP_226922277.1
Coordinates 40018..40272 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHK14_RS20055 (LHK14_20055) 35588..36610 - 1023 WP_226922273.1 ABC transporter substrate-binding protein -
LHK14_RS20060 (LHK14_20060) 36831..37568 + 738 WP_226922274.1 response regulator transcription factor -
LHK14_RS20065 (LHK14_20065) 37565..39664 + 2100 WP_226922275.1 ATP-binding protein -
LHK14_RS20070 (LHK14_20070) 39725..40018 - 294 WP_226922276.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LHK14_RS20075 (LHK14_20075) 40018..40272 - 255 WP_226922277.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
LHK14_RS20080 (LHK14_20080) 40468..42132 - 1665 WP_226922637.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
LHK14_RS20085 (LHK14_20085) 42129..43058 - 930 WP_226922278.1 electron transfer flavoprotein subunit alpha/FixB family protein -
LHK14_RS20090 (LHK14_20090) 43086..43835 - 750 WP_226917574.1 electron transfer flavoprotein subunit beta/FixA family protein -
LHK14_RS20095 (LHK14_20095) 43855..44712 - 858 WP_226922279.1 sugar phosphate isomerase/epimerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..895176 895176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11226.94 Da        Isoelectric Point: 5.8292

>T219285 WP_226922276.1 NZ_CP084753:c40018-39725 [Kinneretia sp. XES5]
MQFHLSVEAEEDIVSIAEHGVRTFGSLVARRYHDELFVMLELIAANPLMARERDEISPPVRIHPFKAHLVVYRIIDDGSI
FVIRIRHGHEDWIGDLL

Download         Length: 294 bp

>T219285 NZ_CP116241:4030893-4031300 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9359.48 Da        Isoelectric Point: 8.5775

>AT219285 WP_226922277.1 NZ_CP084753:c40272-40018 [Kinneretia sp. XES5]
MATMNVSLPDPMKDWVEAQARSGRYSNVSDYVRDLIRRDQARTDKIAEMQRFVDDGIASGVGNRSKDALFAAAVARVESP
RGRD

Download         Length: 255 bp

>AT219285 NZ_CP116241:4030646-4030912 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References