Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-RelB
Location 265127..265659 Replicon chromosome
Accession NZ_CP084752
Organism UNVERIFIED_ORG: Kinneretia sp. XES5

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LHK14_RS01470 Protein ID WP_226919610.1
Coordinates 265390..265659 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag LHK14_RS01465 Protein ID WP_226919609.1
Coordinates 265127..265393 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHK14_RS28135 260528..260656 - 129 WP_256463802.1 hypothetical protein -
LHK14_RS01435 (LHK14_01435) 260672..261112 - 441 WP_226919603.1 arsenic resistance N-acetyltransferase ArsN2 -
LHK14_RS01440 (LHK14_01440) 261109..261462 - 354 WP_226919604.1 helix-turn-helix transcriptional regulator -
LHK14_RS01445 (LHK14_01445) 261655..262938 - 1284 WP_226919605.1 O-acetylhomoserine aminocarboxypropyltransferase -
LHK14_RS01450 (LHK14_01450) 263053..263481 - 429 WP_226919606.1 CoA-binding protein -
LHK14_RS01455 (LHK14_01455) 263545..263982 - 438 WP_226919607.1 CoA-binding protein -
LHK14_RS01460 (LHK14_01460) 264233..265069 + 837 WP_226919608.1 EamA family transporter -
LHK14_RS01465 (LHK14_01465) 265127..265393 + 267 WP_226919609.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LHK14_RS01470 (LHK14_01470) 265390..265659 + 270 WP_226919610.1 Txe/YoeB family addiction module toxin Toxin
LHK14_RS01475 (LHK14_01475) 265664..266479 - 816 WP_226919611.1 enoyl-CoA hydratase -
LHK14_RS01480 (LHK14_01480) 266618..267049 + 432 WP_226919612.1 PaaI family thioesterase -
LHK14_RS01485 (LHK14_01485) 267279..267743 + 465 WP_226919613.1 50S ribosomal protein L13 -
LHK14_RS01490 (LHK14_01490) 267746..268222 + 477 WP_203318588.1 30S ribosomal protein S9 -
LHK14_RS01495 (LHK14_01495) 268353..269306 + 954 WP_226919614.1 agmatinase -
LHK14_RS01500 (LHK14_01500) 269407..270345 + 939 WP_226919615.1 N-acetyl-gamma-glutamyl-phosphate reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10312.80 Da        Isoelectric Point: 9.1662

>T219282 WP_226919610.1 NZ_CP084752:265390-265659 [Kinneretia sp. XES5]
MKICFSPEAWADFTYWTETDRKTVEKIVALIKECRRDPFSGTGKPEPLRGELKGFWSRRITQEHRLVYRVTGSGAAQTLE
IAACRYHYG

Download         Length: 270 bp

>T219282 NZ_CP116241:c3429724-3429617 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9881.19 Da        Isoelectric Point: 5.1239

>AT219282 WP_226919609.1 NZ_CP084752:265127-265393 [Kinneretia sp. XES5]
MKVVSLSELRANIAKHFDSVEADRDELIVTRQNREPMVVMSLADFESWKETIYLTASPANRDHLQRSIRSLDAGKGIGKT
LDDLPPGE

Download         Length: 267 bp

>AT219282 NZ_CP116241:3429781-3429838 [Escherichia coli]
TCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References