Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 6691759..6692312 Replicon chromosome
Accession NZ_CP084742
Organism Pseudomonas sp. L5B5

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LGQ10_RS30800 Protein ID WP_226524166.1
Coordinates 6692019..6692312 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LGQ10_RS30795 Protein ID WP_226524165.1
Coordinates 6691759..6692031 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGQ10_RS30775 (LGQ10_30775) 6686820..6687365 + 546 WP_226524161.1 cytochrome b/b6 domain-containing protein -
LGQ10_RS30780 (LGQ10_30780) 6687409..6688704 + 1296 WP_226524162.1 sialidase family protein -
LGQ10_RS30785 (LGQ10_30785) 6688704..6689315 + 612 WP_226524163.1 hypothetical protein -
LGQ10_RS30790 (LGQ10_30790) 6689365..6691398 + 2034 WP_226524164.1 LTA synthase family protein -
LGQ10_RS30795 (LGQ10_30795) 6691759..6692031 + 273 WP_226524165.1 CopG family ribbon-helix-helix protein Antitoxin
LGQ10_RS30800 (LGQ10_30800) 6692019..6692312 + 294 WP_226524166.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LGQ10_RS30805 (LGQ10_30805) 6692390..6692611 - 222 WP_226524167.1 DUF3077 domain-containing protein -
LGQ10_RS30810 (LGQ10_30810) 6693444..6693647 + 204 WP_095962098.1 helix-turn-helix transcriptional regulator -
LGQ10_RS30815 (LGQ10_30815) 6693740..6695302 + 1563 WP_226524168.1 type I restriction-modification system subunit M -
LGQ10_RS30820 (LGQ10_30820) 6695299..6696504 + 1206 WP_226524169.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11144.76 Da        Isoelectric Point: 4.9313

>T219280 WP_226524166.1 NZ_CP084742:6692019-6692312 [Pseudomonas sp. L5B5]
VPRLILTEGAAQGLERCRQFLVEKGPLIAQRAAQVIERQIARLEEDPEIGRPFPELPELRELIIEFGDSGYVALYRHERV
DDAVYLLAFRHQKEAGY

Download         Length: 294 bp

>T219280 NZ_CP084742:6692019-6692312 [Pseudomonas sp. L5B5]
GTGCCACGATTGATTCTCACCGAAGGTGCTGCGCAAGGGTTGGAGCGTTGTCGCCAGTTTCTAGTCGAGAAAGGCCCGCT
GATCGCTCAACGAGCAGCCCAAGTGATTGAGCGTCAAATTGCTCGACTGGAGGAAGACCCAGAAATCGGTCGTCCCTTTC
CAGAACTGCCGGAGCTGCGCGAGCTGATCATCGAGTTCGGTGATTCGGGTTATGTCGCACTTTATCGGCATGAGCGTGTG
GATGATGCTGTTTACCTACTTGCCTTTCGGCATCAGAAAGAAGCCGGTTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10495.73 Da        Isoelectric Point: 6.4829

>AT219280 WP_226524165.1 NZ_CP084742:6691759-6692031 [Pseudomonas sp. L5B5]
MATSIKIDDELKKRIQHLAGLRQRSSHWIMREAIAQYVEREEAREGFKQEALASWAAYQETGRHLTGQETRAWLNTWGTE
AETELPKCHD

Download         Length: 273 bp

>AT219280 NZ_CP084742:6691759-6692031 [Pseudomonas sp. L5B5]
ATGGCCACTTCTATCAAGATTGATGACGAGCTAAAAAAACGCATTCAGCATCTGGCAGGACTGCGTCAACGTTCGTCCCA
CTGGATTATGCGCGAAGCAATAGCGCAGTACGTCGAGCGCGAGGAAGCCCGTGAGGGTTTCAAACAAGAAGCCTTGGCGT
CTTGGGCGGCGTATCAGGAAACGGGTCGGCATCTGACCGGCCAAGAAACTCGGGCTTGGCTCAATACCTGGGGTACCGAG
GCTGAGACGGAGCTGCCTAAGTGCCACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References