Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 420824..422056 Replicon chromosome
Accession NZ_CP084742
Organism Pseudomonas sp. L5B5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LGQ10_RS01905 Protein ID WP_058433904.1
Coordinates 421484..422056 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LGQ10_RS01900 Protein ID WP_226524487.1
Coordinates 420824..421369 (+) Length 182 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGQ10_RS01875 (LGQ10_01875) 416349..417266 + 918 WP_226524484.1 alpha/beta hydrolase -
LGQ10_RS01880 (LGQ10_01880) 417335..417955 + 621 WP_058433898.1 LysE family translocator -
LGQ10_RS01885 (LGQ10_01885) 418003..418617 - 615 WP_226524485.1 AidA/PixA family protein -
LGQ10_RS01890 (LGQ10_01890) 418996..420174 + 1179 WP_226524486.1 PrpF domain-containing protein -
LGQ10_RS01895 (LGQ10_01895) 420297..420626 - 330 WP_058433902.1 low molecular weight protein tyrosine phosphatase family protein -
LGQ10_RS01900 (LGQ10_01900) 420824..421369 + 546 WP_226524487.1 helix-turn-helix transcriptional regulator Antitoxin
LGQ10_RS01905 (LGQ10_01905) 421484..422056 + 573 WP_058433904.1 HD domain-containing protein Toxin
LGQ10_RS01910 (LGQ10_01910) 422087..422593 + 507 WP_058433905.1 N-acetyltransferase -
LGQ10_RS01915 (LGQ10_01915) 422613..424961 - 2349 WP_226524488.1 penicillin-binding protein 1A -
LGQ10_RS01920 (LGQ10_01920) 425003..426925 - 1923 WP_226524489.1 penicillin-binding protein 2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(10-189)

Antitoxin

Cro/C1-type helix-turn-helix domain

(11-45)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21579.17 Da        Isoelectric Point: 4.8755

>T219277 WP_058433904.1 NZ_CP084742:421484-422056 [Pseudomonas sp. L5B5]
MNSELLTGRLEFLREAERLKDVLRSAHTSSGRQESTAEHSWRLCLMALLLEDQLEDVDLLQVLKMCIVHDLGEALHGDIP
AVEQAAHPDKGQQEREDLQTLASCLDAPARQRLLGLWDEYEAASSAEARTVKALDKLETLLQHNQGRNPADFDYGFNLDY
GRRYTSASPLFEALREQIDRDTQRHLAARK

Download         Length: 573 bp

>T219277 NZ_CP116241:2689184-2689561 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGTTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCTTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 182 a.a.        Molecular weight: 19851.70 Da        Isoelectric Point: 7.4058

>AT219277 WP_226524487.1 NZ_CP084742:420824-421369 [Pseudomonas sp. L5B5]
MFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGQQAMEPAERAKLEQLLAANLSAAADQALARLVNDSPRA
VHLVCDLTHRLLASSPTRAGQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPAALEFFSGHNGSAIVPIAPS
QCRWTRLNLSDGSAVRLVETL

Download         Length: 546 bp

>AT219277 NZ_CP116241:2688763-2689137 [Escherichia coli]
GTGTCAGACACACACCCCGGGACAACGCATCCCGACAACAACAACGACCGCCCCTGGTGGGGGCTCCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCCGACCGCGCCGGTATCAGGGGGCAGT
TTAGCGACGCGGATGCGTATCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAGAGGGCTGACCTGCGAAGCCGACACCCTCGGCAGCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References