Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3413024..3413749 Replicon chromosome
Accession NZ_CP084741
Organism Pectobacterium carotovorum strain A077-S18-O15

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag LHL03_RS15205 Protein ID WP_130640181.1
Coordinates 3413429..3413749 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LHL03_RS15200 Protein ID WP_211046536.1
Coordinates 3413024..3413359 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHL03_RS15170 (LHL03_15170) 3408745..3409671 + 927 WP_211046539.1 hypothetical protein -
LHL03_RS15175 (LHL03_15175) 3409767..3410654 + 888 WP_211046538.1 50S ribosome-binding GTPase -
LHL03_RS15180 (LHL03_15180) 3410838..3410996 + 159 WP_155242703.1 hypothetical protein -
LHL03_RS15185 (LHL03_15185) 3411143..3411976 + 834 WP_226509624.1 hypothetical protein -
LHL03_RS15190 (LHL03_15190) 3412033..3412383 + 351 WP_116156686.1 hypothetical protein -
LHL03_RS15195 (LHL03_15195) 3412511..3412984 + 474 WP_226509625.1 DNA repair protein RadC -
LHL03_RS15200 (LHL03_15200) 3413024..3413359 + 336 WP_211046536.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LHL03_RS15205 (LHL03_15205) 3413429..3413749 + 321 WP_130640181.1 TA system toxin CbtA family protein Toxin
LHL03_RS15210 (LHL03_15210) 3413867..3414700 + 834 WP_226509626.1 DUF4942 domain-containing protein -
LHL03_RS15215 (LHL03_15215) 3415644..3416120 + 477 WP_138256040.1 GNAT family N-acetyltransferase -
LHL03_RS15220 (LHL03_15220) 3416345..3417511 - 1167 Protein_2986 CmlA/FloR family chloramphenicol efflux MFS transporter -
LHL03_RS15225 (LHL03_15225) 3417863..3418084 - 222 WP_010300175.1 acyl carrier protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3392547..3418084 25537


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12120.92 Da        Isoelectric Point: 4.7768

>T219273 WP_130640181.1 NZ_CP084741:3413429-3413749 [Pectobacterium carotovorum]
MQTSPAIPPREDIPCPSPVVVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTTVDILRARRATGLLKA

Download         Length: 321 bp

>T219273 NZ_CP116241:1013077-1013184 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12429.23 Da        Isoelectric Point: 8.0116

>AT219273 WP_211046536.1 NZ_CP084741:3413024-3413359 [Pectobacterium carotovorum]
MPSSDTPEWGLKCAITPRFGARLVQEGNRLHYLADRASIVGTFSKTEAQSLERCFPELIKLLEQKLRTGELNPRQQGCVT
LRCNEWTCKADTLGSFGYVYIVIYPSSAATQ

Download         Length: 336 bp

>AT219273 NZ_CP116241:c1013027-1012964 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References