Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 856874..857366 Replicon chromosome
Accession NZ_CP084741
Organism Pectobacterium carotovorum strain A077-S18-O15

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LHL03_RS03850 Protein ID WP_223806289.1
Coordinates 856874..857125 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LHL03_RS03855 Protein ID WP_138254873.1
Coordinates 857115..857366 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHL03_RS03815 (LHL03_03815) 851899..852381 + 483 WP_039507819.1 GNAT family N-acetyltransferase -
LHL03_RS03820 (LHL03_03820) 852426..853052 - 627 WP_039539927.1 LysE family transporter -
LHL03_RS03825 (LHL03_03825) 853308..854090 - 783 WP_138254869.1 transporter substrate-binding domain-containing protein -
LHL03_RS03830 (LHL03_03830) 854459..855037 - 579 WP_138254870.1 hypothetical protein -
LHL03_RS03835 (LHL03_03835) 855231..855407 - 177 WP_157757028.1 hypothetical protein -
LHL03_RS03840 (LHL03_03840) 855696..856187 + 492 WP_138254871.1 YhfG family protein -
LHL03_RS03845 (LHL03_03845) 856180..856764 + 585 WP_138254872.1 putative adenosine monophosphate-protein transferase Fic -
LHL03_RS03850 (LHL03_03850) 856874..857125 - 252 WP_223806289.1 hypothetical protein Toxin
LHL03_RS03855 (LHL03_03855) 857115..857366 - 252 WP_138254873.1 prevent-host-death protein Antitoxin
LHL03_RS03860 (LHL03_03860) 857496..857966 + 471 Protein_745 hypothetical protein -
LHL03_RS03865 (LHL03_03865) 857966..858295 + 330 WP_223806290.1 DUF1493 family protein -
LHL03_RS03870 (LHL03_03870) 858609..858794 + 186 WP_138254875.1 hypothetical protein -
LHL03_RS03875 (LHL03_03875) 858791..859039 + 249 WP_138254876.1 ogr/Delta-like zinc finger family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9821.41 Da        Isoelectric Point: 10.3055

>T219267 WP_223806289.1 NZ_CP084741:c857125-856874 [Pectobacterium carotovorum]
MSYKLGFEEHALKEFKKLSAPIREQFTKKLKEILQNPHVPANRLHGMADCYKKFIKQPKTDYKRGQFSTRGYFVVQPIYQ
GNE

Download         Length: 252 bp

>T219267 NZ_CP116241:186854-187105 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATATAACTCCCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9044.30 Da        Isoelectric Point: 4.5203

>AT219267 WP_138254873.1 NZ_CP084741:c857366-857115 [Pectobacterium carotovorum]
MSVQPILANAAVSCSDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSQMKGMRVKVDL
DEL

Download         Length: 252 bp

>AT219267 NZ_CP116241:187102-187356 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References