Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 589028..590726 Replicon chromosome
Accession NZ_CP084741
Organism Pectobacterium carotovorum strain A077-S18-O15

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag LHL03_RS02665 Protein ID WP_039522492.1
Coordinates 589028..589957 (-) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag LHL03_RS02670 Protein ID WP_039522494.1
Coordinates 589944..590726 (-) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHL03_RS02645 (LHL03_02645) 584919..587000 - 2082 WP_226509732.1 DUF4034 domain-containing protein -
LHL03_RS02650 (LHL03_02650) 587158..587295 + 138 Protein_511 hypothetical protein -
LHL03_RS02655 (LHL03_02655) 587447..587710 - 264 WP_010286385.1 DUF2798 domain-containing protein -
LHL03_RS02660 (LHL03_02660) 587839..588741 + 903 WP_039543255.1 LysR family transcriptional regulator -
LHL03_RS02665 (LHL03_02665) 589028..589957 - 930 WP_039522492.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LHL03_RS02670 (LHL03_02670) 589944..590726 - 783 WP_039522494.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LHL03_RS02675 (LHL03_02675) 591052..591237 + 186 WP_146044070.1 ash family protein -
LHL03_RS02680 (LHL03_02680) 591188..591649 + 462 WP_138254771.1 hypothetical protein -
LHL03_RS02685 (LHL03_02685) 591646..591855 + 210 WP_039491410.1 helix-turn-helix transcriptional regulator -
LHL03_RS02690 (LHL03_02690) 592455..592658 + 204 WP_035339627.1 AlpA family transcriptional regulator -
LHL03_RS02695 (LHL03_02695) 592684..592950 - 267 WP_138254772.1 helix-turn-helix transcriptional regulator -
LHL03_RS02700 (LHL03_02700) 592947..593792 - 846 WP_138254773.1 replication initiation protein -
LHL03_RS02705 (LHL03_02705) 595043..595420 + 378 WP_138254774.1 plasmid mobilization relaxosome protein MobC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-262)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(2-92)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35195.59 Da        Isoelectric Point: 6.2424

>T219265 WP_039522492.1 NZ_CP084741:c589957-589028 [Pectobacterium carotovorum]
MDQRDIYARQVRLLMTALPYVAKESCFALKGGTAINLFMQDFPRLSVDIDLVYQTFMDRDTDLAAIDDALMRITESLKSQ
PGITAIRQDNKADEKRIIVNTANAQIKIEVSPVWRGLLLPPAEIPVCEQVEMEFGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTRELFDGFLCYLAGHPRPIAELLAPNWDIARIATLYQQEFSGMTQHETSLESLLSVTTLLPQAL
RSHFTTQDKQFLLSYKQNTPDWSLYRYPDIQHLPAIRWKQHNLSALYAKNPAKFSAAVSKLEKVLEQRF

Download         Length: 930 bp

>T219265 NZ_CP116239:c5308693-5307941 [Pseudomonas sp. TUM22785]
ATGGATATCTGGACGACCTGCCAAGGCTCGGAACGGATCAGGCCCTTGCGTGGCCGCCTGGTGCGCCTGGTGGAGAGCCA
GGAGCAGGTGGCGACCTTGCAGCTGGTGGATAACCTCGCCGAGCAGGCGTTGCTGGAGGAGCTCATCGAGACCAGCAAGC
CGCCGCTGCCCCGCAGCGCCGAACCGCTGCACTACCTGCTGAAGACCCCGTTCCGCTACCCGCCGCTGCGCTGGGGATCG
CGCTTCGGCACCGTTCATGAGCCCAGCCTGTTCTATGCCGCATCACGCCTGGAAACCGCCATGGCCGAAGGGGCCTTCTA
CCGCTTCGTGCTGTGGAGCGGCATGGCGGTGCCGCCGCCCAGCGGGCGCATCCTGTCCGAGCATTCGTCCTTCGAGGCGC
GCTTCCAGGTCGAGCGCGGTGTGCAACTGCAATTGCCGCCTTTCGATGCCCACGACGAAGCACTCGCCGACCCGGTGGAC
TACCGCACCAGCCAGGCGCTGGGTGCCGCCATGCGCGCTGCGGGGGTCGAGGCCTTCGAGTACCGTTCCGCGCGTTGCCC
GTTGCAGGGCACCAATATCGCCCTGTTCACCCCTGAAGCCTTCACCGAGCGGCGGCCGCGCAATCTCACGCCCTGGCTCT
GCGAAACCACCGCCGAATACGTCGCCTTCAAGCATGCCCAGGCACCGGACACGCCGCGCCTGTTCCGCATGACCCAGTTC
CTTGTCGACGGTCGCTTGCCGCAGCCGGCATGA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29345.67 Da        Isoelectric Point: 9.0909

>AT219265 WP_039522494.1 NZ_CP084741:c590726-589944 [Pectobacterium carotovorum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPIWVAGLT
SIALQGYSHYTELGKPQVWLTIPAYITLPGWFAAFEKSATFVVLYTSGLSVDVMPFTTELRIGDRRLTGSVPELAAYEIA
SGVPTQISFEHADALFQGLHLLSPRKLQALLSASRSVKTNRVMLYLAQRNGHPYFQYLDKSGIEVGAGKRQIVPGGWLEP
DYQITVPREFKSKGIEDGSA

Download         Length: 783 bp

>AT219265 NZ_CP116239:c5309101-5308730 [Pseudomonas sp. TUM22785]
ATGAGCGCCCTCAGCCGCCCCACCCTCGATCCCGATGCCGTATTGGCCAAGGCCCTGCTCAATACCCGTGAGCAACTGGG
GCTGACCCAGCAGCAACTGGCCGACATCGTCGGGGTGCACCGTACCGCCATCACCCGCTGGGCGGACAGCGGCGGCATCC
GCCCACAGAGCAAGACCGGCGAGCTGGCGCTGCTGCTGATCCGCGCCTACCGCGCCCTGTTCGCCTTGTTCGGCGGCAAC
CTCGACGACATGCGCCATTTCCTGCGCACCGAGAACCGCCACCTGGGTGCCGTGCCCCTCGAACTGATGGCCCAGGTGCA
GGGTCTGGTAAGGGTGGTGGAGTACCTGGACGCCATACGCGGCAAGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References