Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1513998..1514782 Replicon chromosome
Accession NZ_CP084740
Organism Dickeya zeae strain A586-S18-A17

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag LHK94_RS06735 Protein ID WP_226511315.1
Coordinates 1513998..1514492 (-) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag LHK94_RS06740 Protein ID WP_110371294.1
Coordinates 1514489..1514782 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHK94_RS06720 (LHK94_06725) 1509279..1510988 - 1710 WP_264183315.1 E2/UBC family protein -
LHK94_RS06725 (LHK94_06730) 1511054..1512355 - 1302 WP_226511313.1 hypothetical protein -
LHK94_RS06730 (LHK94_06735) 1512352..1513434 - 1083 WP_226511314.1 CBASS cGAMP-activated phospholipase -
LHK94_RS06735 (LHK94_06740) 1513998..1514492 - 495 WP_226511315.1 GNAT family N-acetyltransferase Toxin
LHK94_RS06740 (LHK94_06745) 1514489..1514782 - 294 WP_110371294.1 DUF1778 domain-containing protein Antitoxin
LHK94_RS06745 (LHK94_06750) 1514890..1515390 - 501 WP_226511316.1 serine acetyltransferase -
LHK94_RS06750 (LHK94_06755) 1515420..1516814 - 1395 WP_226511317.1 DUF4832 domain-containing protein -
LHK94_RS06755 (LHK94_06760) 1516852..1517259 - 408 WP_226099917.1 hypothetical protein -
LHK94_RS06760 (LHK94_06765) 1517306..1518409 - 1104 WP_012883267.1 glycosyltransferase family 4 protein -
LHK94_RS06765 (LHK94_06770) 1518411..1519622 - 1212 WP_226511318.1 glycosyltransferase family 4 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17907.90 Da        Isoelectric Point: 8.1389

>T219251 WP_226511315.1 NZ_CP084740:c1514492-1513998 [Dickeya zeae]
MISAPEPLRTEHVLSSFCCSVESMDNWLKQRAMKNQVSGASRTFVCCDDAKVLAYYSLASSAVMTNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEARDFYLRVGFEPSPIDPMMLMVTLRDLVG
SLSI

Download         Length: 495 bp

>T219251 NZ_CP116231:2424978-2425346 [Fusobacterium nucleatum]
ATGTACAAAGTTGGGTTTTATTTAAAAAATGGAAAATCTGATATAATAGAATATTTAGACAAATTAAAAATAAAATCTGA
AAAAAGTAAAGAGGCAAGAATAATAAGAAATAAAATATTAAGTTATATCAAGTCATTAGAGCTATATGGAACAAGAGTTG
GAGAACCTATTGTAAAACATATTGAAGATAATATTTGGGAGCTAAGACCATTAAACAATAGAATATTTTTCTTTTATTTT
AAAGATAATAAATTTATTTTACTACATTATTTTATAAAAAAGACTAATAAAACACCTAAAAAAGAAATAGAAGAAGCTAA
AAATAGAATGAATGATTTTATAGCAAGGAGTGATAAGAATGTCAAATAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10972.56 Da        Isoelectric Point: 9.8078

>AT219251 WP_110371294.1 NZ_CP084740:c1514782-1514489 [Dickeya zeae]
MPATNNVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLTRLDQAPSPN
AELRKTMQTPAPWELKK

Download         Length: 294 bp

>AT219251 NZ_CP116231:2425336-2425623 [Fusobacterium nucleatum]
ATGTCAAATAATGAATATTTAGATTTTGATGATTATTTTAATGATGAAACAAAAGTAAGTAAAGAGGATAAGGCAATAAT
AGAATTAGAAACTTTATTGATTGGTAAAATGATAGAAATTAGAGAGAAAAAAGGTTTAACTCAAAGACAACTTGCTGAAT
TAACAGGGATGAAACAACCTGCCATAGCAAGACTTGAGAAACTACAAACAATTCCTCATCTAACAACTTTAATAAAATTT
TTAACACCATTAGGTTATAAATTATCAATAGTTCCTATTGAGAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References