Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 901029..901591 Replicon chromosome
Accession NZ_CP084736
Organism Gordonia sp. WA4-43

Toxin (Protein)


Gene name relE Uniprot ID A0A6G7W718
Locus tag LEL84_RS04165 Protein ID WP_055477308.1
Coordinates 901029..901319 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6G7W6R5
Locus tag LEL84_RS04170 Protein ID WP_055477309.1
Coordinates 901316..901591 (-) Length 92 a.a.

Genomic Context


LEL84_RS04145LEL84_RS04150LEL84_RS04155LEL84_RS04160LEL84_RS04185LEL84_RS04190LEL84_RS04140LEL84_RS04165LEL84_RS04170LEL84_RS04175LEL84_RS04180LEL84_RS04195LEL84_RS04200
Location: 896980..899040 (2061 bp)
Type: Others
Protein ID: WP_226513398.1
Location: 899075..899314 (240 bp)
Type: Others
Protein ID: WP_055477305.1
Location: 899903..900136 (234 bp)
Type: Others
Protein ID: WP_226513399.1
Location: 900804..901010 (207 bp)
Type: Others
Protein ID: WP_055477311.1
Location: 903263..904024 (762 bp)
Type: Others
Protein ID: WP_139104661.1
Location: 904079..904384 (306 bp)
Type: Others
Protein ID: WP_068970442.1
Location: 896096..896695 (600 bp)
Type: Others
Protein ID: WP_226513397.1
Location: 901029..901319 (291 bp)
Type: Toxin
Protein ID: WP_055477308.1
Location: 901316..901591 (276 bp)
Type: Antitoxin
Protein ID: WP_055477309.1
Location: 901711..902331 (621 bp)
Type: Others
Protein ID: WP_223258858.1
Location: 902328..902855 (528 bp)
Type: Others
Protein ID: WP_065631669.1
Location: 904436..904816 (381 bp)
Type: Others
Protein ID: WP_065631666.1
Location: 904965..905870 (906 bp)
Type: Others
Protein ID: WP_065631665.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LEL84_RS04140 (LEL84_04140)896096..896695-600WP_226513397.1hypothetical protein-
LEL84_RS04145 (LEL84_04145)896980..899040+2061WP_226513398.1DEAD/DEAH box helicase family protein-
LEL84_RS04150 (LEL84_04150)899075..899314+240WP_055477305.1hypothetical protein-
LEL84_RS04155 (LEL84_04155)899903..900136+234WP_226513399.1hypothetical protein-
LEL84_RS04160 (LEL84_04160)900804..901010+207WP_055477311.1hypothetical protein-
LEL84_RS04165 (LEL84_04165)901029..901319-291WP_055477308.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LEL84_RS04170 (LEL84_04170)901316..901591-276WP_055477309.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
LEL84_RS04175 (LEL84_04175)901711..902331-621WP_223258858.1TetR/AcrR family transcriptional regulator-
LEL84_RS04180 (LEL84_04180)902328..902855-528WP_065631669.1GNAT family N-acetyltransferase-
LEL84_RS04185 (LEL84_04185)903263..904024+762WP_139104661.1hypothetical protein-
LEL84_RS04190 (LEL84_04190)904079..904384+306WP_068970442.1hypothetical protein-
LEL84_RS04195 (LEL84_04195)904436..904816-381WP_065631666.1SRPBCC family protein-
LEL84_RS04200 (LEL84_04200)904965..905870-906WP_065631665.1RNA polymerase sigma-70 factor-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 10938.40 Da        Isoelectric Point: 9.7360

>T219242 WP_055477308.1 NZ_CP084736:c901319-901029 [Gordonia sp. WA4-43]
MSDAPTDSSAPYRVEVASPARRDLQRLPSRIVHAVIEFISGPLAENPHRLSKPLRDDLADLHSARRGDYRILLRIDDPNH
TIVIVRIDHRAHAYRT

Download         Length: 291 bp

>T219242 NZ_CP116223:3642757-3643143 [Proteus mirabilis]
ATGGTTATTTATAAAACAAAGATGTTCAAAAATAGTTTCAAAAAAATAACGCTTACGAATGCAGAACTAATAGCTATTGC
TACCGAAGTCCTTGCAGGACAATTTGAGGCAGATCTAGGTGGTGGTGTTATCAAGAAACGTGCCTGTATCCAAGGAAAAG
GTAAAAGTAGCGGAATTAGAACAATTATATTTTATAAGCAAGGGAATAATTTATTCTTTGCTGATGGTTGGAAAAAATCG
AGTTTAAGCTCTAAAAAAACCAAAGAGATCACAGATGATGAACTTGAGTCCTATAAAGATCTAGCAAAAGATCTCTTCAA
TGCAAATCAAAATAAAATAGATAAAATGATTGCACTAGGCCTTTTAACAGAGGTTAAATATGACTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9718.86 Da        Isoelectric Point: 4.3809

>AT219242 WP_055477309.1 NZ_CP084736:c901591-901316 [Gordonia sp. WA4-43]
MTTVPLGEAKDKLSALVDSAESTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGVRDDVATADAEYAAGETVSID
DLRAEHGMPPK

Download         Length: 276 bp

>AT219242 NZ_CP116223:3643136-3643456 [Proteus mirabilis]
ATGACTGATAAAATGAAAGAAATGCTAAAATTTGCACAAGAAATGGAAGATGCAGGAGTCACTGATGGCAGTACAACTAA
ACGTATTGCCGCCAGAATAAAAGCGAAAGAATTACAAGCTAAGTATAAACATCCTACCCCTATGACAGGTGAAGATATAA
AAAGGATCCGTGAGCAAAATAATATCTCTCAATCTTCCCTTGCTTTGATATTGAATATGACTAAAGAAAGCGTTTCTAAG
TGGGAAAGAAACGAAATTAAGCCCAATGGTGCCGCACTACGACTTCTTCATTTAATAGATAAAAAAATATTATTCATCTA
G

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A6G7W718


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A6G7W6R5

References