Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) VapXD/-
Location 5528760..5529238 Replicon chromosome
Accession NC_008786
Organism Verminephrobacter eiseniae EF01-2

Toxin (Protein)


Gene name VapD Uniprot ID A1WSS3
Locus tag VEIS_RS24230 Protein ID WP_011812658.1
Coordinates 5528960..5529238 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name VapX Uniprot ID -
Locus tag VEIS_RS24225 Protein ID WP_041951271.1
Coordinates 5528760..5528960 (+) Length 67 a.a.

Genomic Context

VEIS_RS24215VEIS_RS24220VEIS_RS24225VEIS_RS24230VEIS_RS24235VEIS_RS29445
Location: 5525513..5527939 (2427 bp)
Type: Others
Protein ID: WP_011812655.1
Location: 5527991..5528485 (495 bp)
Type: Others
Protein ID: WP_041950329.1
Location: 5528760..5528960 (201 bp)
Type: Antitoxin
Protein ID: WP_041951271.1
Location: 5528960..5529238 (279 bp)
Type: Toxin
Protein ID: WP_011812658.1
Location: 5529409..5529846 (438 bp)
Type: Others
Protein ID: WP_041950330.1
Location: 5530059..5530661 (603 bp)
Type: Others
Protein ID: WP_198137936.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VEIS_RS242155525513..5527939+2427WP_011812655.1ABC transporter ATP-binding protein/permease-
VEIS_RS242205527991..5528485+495WP_041950329.1DUF1854 domain-containing protein-
VEIS_RS242255528760..5528960+201WP_041951271.1DUF5397 domain-containing proteinAntitoxin
VEIS_RS242305528960..5529238+279WP_011812658.1virulence factorToxin
VEIS_RS242355529409..5529846+438WP_041950330.1hypothetical protein-
VEIS_RS294455530059..5530661+603WP_198137936.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Virulence-associated protein D / CRISPR associated protein Cas2

(1-87)

Antitoxin

Protein of unknown function DUF5397

(4-66)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10501.05 Da        Isoelectric Point: 8.4848

>T21924 WP_011812658.1 NC_008786:5528960-5529238 [Verminephrobacter eiseniae EF01-2]
MYALAFDLVVADTAKHHPKGVTQAYTEIGAVLGEYGFRRVQGSLYVTDDENMANLFLAIQALRTRMWFPKSVRDIRAFRI
EQWSDFTAVVKS

Download         Length: 279 bp

>T21924 NC_008786:5528960-5529238 [Verminephrobacter eiseniae EF01-2]
ATGTACGCGCTAGCTTTCGACCTGGTGGTGGCCGACACTGCCAAGCATCACCCCAAGGGCGTGACACAGGCGTATACCGA
GATTGGCGCGGTGCTTGGCGAGTATGGCTTTCGCCGCGTACAGGGTAGCCTGTACGTCACCGATGACGAGAACATGGCGA
ACCTGTTCCTTGCCATCCAGGCGCTGAGAACCCGGATGTGGTTCCCAAAGTCCGTGCGCGATATCCGCGCTTTCCGTATC
GAGCAGTGGTCTGACTTCACTGCCGTGGTGAAGTCGTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7383.40 Da        Isoelectric Point: 4.6436

>AT21924 WP_041951271.1 NC_008786:5528760-5528960 [Verminephrobacter eiseniae EF01-2]
MQTAITPPAVPVGEFKSFGPLGPKYEVGRAIRQLGDGDWMIEITMIETGEKAEYRWSHLIDDPQAH

Download         Length: 201 bp

>AT21924 NC_008786:5528760-5528960 [Verminephrobacter eiseniae EF01-2]
ATGCAGACAGCCATCACACCGCCCGCCGTTCCGGTCGGCGAATTCAAGAGCTTTGGGCCGTTGGGCCCGAAATACGAAGT
GGGTCGAGCCATTCGCCAGTTGGGCGATGGGGACTGGATGATCGAGATCACGATGATCGAAACGGGCGAGAAAGCGGAAT
ACCGTTGGTCGCATCTGATCGATGACCCGCAGGCTCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA1WSS3

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References