Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-paaA/-
Location 4782621..4783108 Replicon chromosome
Accession NC_008786
Organism Verminephrobacter eiseniae EF01-2

Toxin (Protein)


Gene name relE Uniprot ID A1WQY7
Locus tag VEIS_RS20975 Protein ID WP_011812030.1
Coordinates 4782809..4783108 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag VEIS_RS27075 Protein ID WP_011812029.1
Coordinates 4782621..4782809 (+) Length 63 a.a.

Genomic Context

VEIS_RS20970VEIS_RS29220VEIS_RS29225VEIS_RS27075VEIS_RS20975VEIS_RS20980VEIS_RS20960VEIS_RS20965VEIS_RS20985
Location: 4779995..4781299 (1305 bp)
Type: Others
Protein ID: WP_011812027.1
Location: 4781342..4781527 (186 bp)
Type: Others
Protein ID: WP_157048621.1
Location: 4782185..4782346 (162 bp)
Type: Others
Protein ID: WP_157048622.1
Location: 4782621..4782809 (189 bp)
Type: Antitoxin
Protein ID: WP_011812029.1
Location: 4782809..4783108 (300 bp)
Type: Toxin
Protein ID: WP_011812030.1
Location: 4783445..4785748 (2304 bp)
Type: Others
Protein ID: WP_041950241.1
Location: 4778029..4778667 (639 bp)
Type: Others
Protein ID: WP_011812025.1
Location: 4778669..4779784 (1116 bp)
Type: Others
Protein ID: WP_011812026.1
Location: 4785813..4786046 (234 bp)
Type: Others
Protein ID: WP_041950242.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VEIS_RS209604778029..4778667-639WP_011812025.1LysE family transporter-
VEIS_RS209654778669..4779784-1116WP_011812026.1alanine racemase-
VEIS_RS209704779995..4781299+1305WP_011812027.1lysophospholipid transporter LplT-
VEIS_RS292204781342..4781527+186WP_157048621.1hypothetical protein-
VEIS_RS292254782185..4782346+162WP_157048622.1hypothetical protein-
VEIS_RS270754782621..4782809+189WP_011812029.1hypothetical proteinAntitoxin
VEIS_RS209754782809..4783108+300WP_011812030.1type II toxin-antitoxin system RelE/ParE family toxinToxin
VEIS_RS209804783445..4785748+2304WP_041950241.1Ig-like domain-containing protein-
VEIS_RS209854785813..4786046-234WP_041950242.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11650.37 Da        Isoelectric Point: 6.9771

>T21923 WP_011812030.1 NC_008786:4782809-4783108 [Verminephrobacter eiseniae EF01-2]
MLPIFWLETADTDLADITQYIGLRDINAAERMWHRLRNCVLPLSEHPYLYRISERVPGLREIVAHPNYLVLYRVTATRIE
VVNVVHTRREFPQHSNDGP

Download         Length: 300 bp

>T21923 NC_008786:4782809-4783108 [Verminephrobacter eiseniae EF01-2]
ATGCTGCCGATCTTCTGGCTAGAGACAGCCGACACCGATCTGGCCGACATCACACAATACATCGGCCTGCGCGACATCAA
TGCAGCAGAGCGCATGTGGCACCGCCTGCGCAACTGCGTCCTGCCGCTGTCAGAGCACCCATACCTATACCGCATCAGCG
AGCGTGTTCCCGGTCTGCGCGAAATCGTCGCGCATCCCAACTACCTCGTGTTGTACCGGGTCACAGCGACCCGCATCGAA
GTCGTGAACGTGGTGCATACCCGTCGTGAATTCCCCCAGCACTCCAATGACGGCCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7049.91 Da        Isoelectric Point: 6.4573

>AT21923 WP_011812029.1 NC_008786:4782621-4782809 [Verminephrobacter eiseniae EF01-2]
MSTDLSPIVSEFETSDQQASYTEWLRAKVAASLADPRPAIPHDEVERRMAQRLAQLRKHQVS

Download         Length: 189 bp

>AT21923 NC_008786:4782621-4782809 [Verminephrobacter eiseniae EF01-2]
ATGAGCACCGATCTTTCCCCGATCGTCTCGGAGTTCGAAACCTCCGACCAGCAAGCCAGCTACACCGAATGGCTACGCGC
CAAGGTCGCGGCCAGTCTTGCCGACCCGCGCCCGGCTATTCCTCATGATGAGGTAGAGCGGCGTATGGCTCAACGACTGG
CTCAGCTACGCAAGCACCAAGTGTCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA1WQY7

Antitoxin

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Source
ID
Structure
No matching records found

References