Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3421349..3421865 Replicon chromosome
Accession NZ_CP084714
Organism Pseudomonas asiatica strain P1

Toxin (Protein)


Gene name relE Uniprot ID F8G1E7
Locus tag LG197_RS15690 Protein ID WP_003259987.1
Coordinates 3421584..3421865 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LG197_RS15685 Protein ID WP_096010237.1
Coordinates 3421349..3421594 (+) Length 82 a.a.

Genomic Context

LG197_RS15675LG197_RS15680LG197_RS15685LG197_RS15690LG197_RS15705LG197_RS15710LG197_RS15665LG197_RS15670LG197_RS15695LG197_RS15700
Location: 3418775..3419968 (1194 bp)
Type: Others
Protein ID: WP_196184775.1
Location: 3419999..3421105 (1107 bp)
Type: Others
Protein ID: WP_196184774.1
Location: 3421349..3421594 (246 bp)
Type: Antitoxin
Protein ID: WP_096010237.1
Location: 3421584..3421865 (282 bp)
Type: Toxin
Protein ID: WP_003259987.1
Location: 3423588..3424892 (1305 bp)
Type: Others
Protein ID: WP_013972046.1
Location: 3424923..3426164 (1242 bp)
Type: Others
Protein ID: WP_196184772.1
Location: 3416776..3417318 (543 bp)
Type: Others
Protein ID: WP_038409286.1
Location: 3417426..3418412 (987 bp)
Type: Others
Protein ID: WP_196184776.1
Location: 3421904..3422299 (396 bp)
Type: Others
Protein ID: WP_023662326.1
Location: 3422388..3423296 (909 bp)
Type: Others
Protein ID: WP_013972045.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LG197_RS15665 (LG197_15660)3416776..3417318-543WP_038409286.1WYL domain-containing protein-
LG197_RS15670 (LG197_15665)3417426..3418412-987WP_196184776.1zinc-binding dehydrogenase-
LG197_RS15675 (LG197_15670)3418775..3419968+1194WP_196184775.1MFS transporter-
LG197_RS15680 (LG197_15675)3419999..3421105+1107WP_196184774.1alkene reductase-
LG197_RS15685 (LG197_15680)3421349..3421594+246WP_096010237.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
LG197_RS15690 (LG197_15685)3421584..3421865+282WP_003259987.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LG197_RS15695 (LG197_15690)3421904..3422299-396WP_023662326.1hypothetical protein-
LG197_RS15700 (LG197_15695)3422388..3423296-909WP_013972045.1LysR family transcriptional regulator-
LG197_RS15705 (LG197_15700)3423588..3424892+1305WP_013972046.1MFS transporter-
LG197_RS15710 (LG197_15705)3424923..3426164+1242WP_196184772.1Zn-dependent hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-76)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10909.78 Da        Isoelectric Point: 10.7594

>T219223 WP_003259987.1 NZ_CP084714:3421584-3421865 [Pseudomonas asiatica]
MTYKLEFLPSALKEWGKLGHTVREQIKKKLAERLQSPKVQADALRDLPNHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
RERSEVYRSAQKR

Download         Length: 282 bp

>T219223 NZ_CP116214:4525725-4525943 [Klebsiella michiganensis]
ATGTCTGATAAAACATTAACCAAAATAGACTATTTGATGCGTTTACGACGCTGTCAGACAATTGATACGCTGGAGCGCGT
AATTGAAAAAAATAAATATGAACTTTCCGATAATGAACTGGCGGTATTTTACTCTGCGGCCGATCATCGTCTTGCAGAGC
TGACGATGAATAAACTGTATGACAAGATCCCCCCTTCAGTCTGGAAATTTATCCGCTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8749.18 Da        Isoelectric Point: 4.3611

>AT219223 WP_096010237.1 NZ_CP084714:3421349-3421594 [Pseudomonas asiatica]
MQNIFADVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELGELAKSRLGEKGVPVSLDD
L

Download         Length: 246 bp

>AT219223 NZ_CP116214:4525324-4525698 [Klebsiella michiganensis]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCGCAGCTTAAATTTCTCTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTGGAAGAGAGCAACCACGGCTGGGTTAATGATCCAACCTCGGCTGTCAATCTTCAACTTAATGAATTGATCGAGC
ACATTGCCGCGTTTGCACTTAATTATAAAATTAAGTACGCAGAGGATAATAAGCTGATTACCCAGATTGACGAATATCTG
GATGACACTTTCGTCTTGTTCAGCAACTACGGCATTAACAGCGCAGATCTGCAGAAATGGCGTAAATCTGGCAATCGGTT
ATTCCGCTGCTTTGTCAACGCCAGTCGGGAAAACCCGGCCAGTCTTTCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBF8G1E7

Antitoxin

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Source
ID
Structure
No matching records found

References