Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 4579026..4580065 | Replicon | chromosome |
| Accession | NC_008786 | ||
| Organism | Verminephrobacter eiseniae EF01-2 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | VEIS_RS20160 | Protein ID | WP_011811855.1 |
| Coordinates | 4579490..4580065 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | A1WQG0 |
| Locus tag | VEIS_RS20155 | Protein ID | WP_011811854.1 |
| Coordinates | 4579026..4579493 (+) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VEIS_RS20130 | 4574174..4575073 | - | 900 | WP_011811849.1 | serine/threonine-protein phosphatase | - |
| VEIS_RS20135 | 4575070..4576092 | - | 1023 | WP_011811850.1 | serine/threonine protein kinase | - |
| VEIS_RS20140 | 4576169..4577086 | + | 918 | WP_011811851.1 | YicC family protein | - |
| VEIS_RS20145 | 4577297..4578556 | + | 1260 | WP_011811852.1 | site-specific integrase | - |
| VEIS_RS20150 | 4578609..4578920 | + | 312 | WP_041950223.1 | DNA-binding protein | - |
| VEIS_RS20155 | 4579026..4579493 | + | 468 | WP_011811854.1 | helix-turn-helix domain-containing protein | Antitoxin |
| VEIS_RS20160 | 4579490..4580065 | + | 576 | WP_011811855.1 | PIN domain-containing protein | Toxin |
| VEIS_RS20165 | 4580135..4580539 | - | 405 | WP_011811856.1 | hypothetical protein | - |
| VEIS_RS20170 | 4580576..4581583 | - | 1008 | WP_049773979.1 | integrase domain-containing protein | - |
| VEIS_RS20175 | 4582360..4582887 | + | 528 | WP_011811858.1 | hypothetical protein | - |
| VEIS_RS20180 | 4582999..4584054 | + | 1056 | WP_011811859.1 | Fic family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21375.54 Da Isoelectric Point: 5.2492
>T21922 WP_011811855.1 NC_008786:4579490-4580065 [Verminephrobacter eiseniae EF01-2]
MRQSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSTQIHEEWKRNLLINRPDLRPDQVDRTSALMDQAIPDGLVSDY
EALIAGLRLPDPDDCHVLAAAIRCGASVIVTFNEKDFPQAALAPFGIEAQHPDLFIDNLFDLDAAAVVSAAQKQRAQLKS
PPLDVDRYLDALLRQGLVQTVKALSTYRTIL
MRQSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSTQIHEEWKRNLLINRPDLRPDQVDRTSALMDQAIPDGLVSDY
EALIAGLRLPDPDDCHVLAAAIRCGASVIVTFNEKDFPQAALAPFGIEAQHPDLFIDNLFDLDAAAVVSAAQKQRAQLKS
PPLDVDRYLDALLRQGLVQTVKALSTYRTIL
Download Length: 576 bp
>T21922 NC_008786:4579490-4580065 [Verminephrobacter eiseniae EF01-2]
ATGAGGCAGTCGCCATTCACGGCCGTCTATGACGCATGCGTGTTGTACCCGGCGCCGTTACGGGACTTTCTCATGTGGCT
GGGTCTTTCCGGCCGCTTCCGGGCACGTTGGAGTACGCAGATCCACGAGGAATGGAAACGCAACCTGCTGATCAACCGCC
CGGATCTTCGCCCCGATCAGGTTGACCGCACATCGGCATTGATGGACCAGGCCATCCCGGATGGCTTGGTCTCGGATTAC
GAAGCGCTCATCGCCGGATTGCGCCTGCCAGACCCGGACGACTGCCATGTCCTGGCTGCGGCCATCCGTTGCGGCGCCAG
CGTCATCGTGACCTTCAACGAAAAGGATTTTCCGCAGGCAGCGCTCGCGCCCTTCGGCATCGAGGCGCAGCATCCAGACC
TTTTCATCGACAACCTGTTCGACCTGGATGCGGCAGCAGTGGTATCGGCAGCGCAGAAGCAGCGGGCGCAGTTGAAGAGC
CCGCCACTGGATGTGGATCGCTACCTCGACGCGTTGTTGCGACAAGGTCTGGTCCAGACCGTCAAGGCACTTTCGACCTA
TCGGACCATTCTCTGA
ATGAGGCAGTCGCCATTCACGGCCGTCTATGACGCATGCGTGTTGTACCCGGCGCCGTTACGGGACTTTCTCATGTGGCT
GGGTCTTTCCGGCCGCTTCCGGGCACGTTGGAGTACGCAGATCCACGAGGAATGGAAACGCAACCTGCTGATCAACCGCC
CGGATCTTCGCCCCGATCAGGTTGACCGCACATCGGCATTGATGGACCAGGCCATCCCGGATGGCTTGGTCTCGGATTAC
GAAGCGCTCATCGCCGGATTGCGCCTGCCAGACCCGGACGACTGCCATGTCCTGGCTGCGGCCATCCGTTGCGGCGCCAG
CGTCATCGTGACCTTCAACGAAAAGGATTTTCCGCAGGCAGCGCTCGCGCCCTTCGGCATCGAGGCGCAGCATCCAGACC
TTTTCATCGACAACCTGTTCGACCTGGATGCGGCAGCAGTGGTATCGGCAGCGCAGAAGCAGCGGGCGCAGTTGAAGAGC
CCGCCACTGGATGTGGATCGCTACCTCGACGCGTTGTTGCGACAAGGTCTGGTCCAGACCGTCAAGGCACTTTCGACCTA
TCGGACCATTCTCTGA
Antitoxin
Download Length: 156 a.a. Molecular weight: 17117.67 Da Isoelectric Point: 6.3392
>AT21922 WP_011811854.1 NC_008786:4579026-4579493 [Verminephrobacter eiseniae EF01-2]
MSTAALVNVSLPVEREVQAALEGQRALAAFLATRVETQQIQIFDDKNQAHRVELPTSALRLLVDILAELAEGNAVKVVPV
HAELTTQEAADMLNVSRPHLVKLLEEGALPFHRAGKHRRVRFVDLMQFKARRDQASEDAMAALAKQAQELGMGYE
MSTAALVNVSLPVEREVQAALEGQRALAAFLATRVETQQIQIFDDKNQAHRVELPTSALRLLVDILAELAEGNAVKVVPV
HAELTTQEAADMLNVSRPHLVKLLEEGALPFHRAGKHRRVRFVDLMQFKARRDQASEDAMAALAKQAQELGMGYE
Download Length: 468 bp
>AT21922 NC_008786:4579026-4579493 [Verminephrobacter eiseniae EF01-2]
ATGTCCACCGCTGCCCTTGTCAACGTGTCGCTGCCCGTCGAGCGTGAGGTGCAGGCCGCCCTGGAAGGACAGCGAGCCTT
GGCCGCCTTCCTGGCCACGCGCGTGGAAACGCAGCAGATCCAGATTTTCGACGACAAGAACCAAGCCCATCGGGTGGAGC
TGCCCACGTCCGCGCTGCGCCTGCTGGTGGACATCCTGGCGGAGCTCGCCGAAGGCAATGCCGTCAAGGTGGTGCCGGTC
CATGCCGAACTCACGACCCAGGAGGCCGCCGACATGCTCAATGTGTCCCGGCCACACTTGGTCAAGCTACTCGAAGAGGG
TGCACTTCCCTTCCACAGGGCCGGCAAGCATCGGCGCGTCCGCTTTGTCGACCTGATGCAGTTCAAGGCCCGGAGAGACC
AAGCCAGCGAAGACGCCATGGCGGCGTTGGCGAAACAGGCTCAGGAACTGGGCATGGGCTACGAATGA
ATGTCCACCGCTGCCCTTGTCAACGTGTCGCTGCCCGTCGAGCGTGAGGTGCAGGCCGCCCTGGAAGGACAGCGAGCCTT
GGCCGCCTTCCTGGCCACGCGCGTGGAAACGCAGCAGATCCAGATTTTCGACGACAAGAACCAAGCCCATCGGGTGGAGC
TGCCCACGTCCGCGCTGCGCCTGCTGGTGGACATCCTGGCGGAGCTCGCCGAAGGCAATGCCGTCAAGGTGGTGCCGGTC
CATGCCGAACTCACGACCCAGGAGGCCGCCGACATGCTCAATGTGTCCCGGCCACACTTGGTCAAGCTACTCGAAGAGGG
TGCACTTCCCTTCCACAGGGCCGGCAAGCATCGGCGCGTCCGCTTTGTCGACCTGATGCAGTTCAAGGCCCGGAGAGACC
AAGCCAGCGAAGACGCCATGGCGGCGTTGGCGAAACAGGCTCAGGAACTGGGCATGGGCTACGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|