Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VapB |
| Location | 2218481..2219082 | Replicon | chromosome |
| Accession | NZ_CP084713 | ||
| Organism | Mycolicibacterium phocaicum strain RL-HY01 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | LHJ73_RS10585 | Protein ID | WP_226521555.1 |
| Coordinates | 2218481..2218882 (-) | Length | 134 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | LHJ73_RS10590 | Protein ID | WP_226521556.1 |
| Coordinates | 2218879..2219082 (-) | Length | 68 a.a. |
Genomic Context
Location: 2213496..2214095 (600 bp)
Type: Others
Protein ID: WP_226521552.1
Type: Others
Protein ID: WP_226521552.1
Location: 2214088..2217366 (3279 bp)
Type: Others
Protein ID: WP_226521553.1
Type: Others
Protein ID: WP_226521553.1
Location: 2217359..2218498 (1140 bp)
Type: Others
Protein ID: WP_226521554.1
Type: Others
Protein ID: WP_226521554.1
Location: 2218481..2218882 (402 bp)
Type: Toxin
Protein ID: WP_226521555.1
Type: Toxin
Protein ID: WP_226521555.1
Location: 2218879..2219082 (204 bp)
Type: Antitoxin
Protein ID: WP_226521556.1
Type: Antitoxin
Protein ID: WP_226521556.1
Location: 2219681..2223010 (3330 bp)
Type: Others
Protein ID: WP_207546857.1
Type: Others
Protein ID: WP_207546857.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LHJ73_RS10570 (LHJ73_10570) | 2213496..2214095 | + | 600 | WP_226521552.1 | DUF4194 domain-containing protein | - |
| LHJ73_RS10575 (LHJ73_10575) | 2214088..2217366 | + | 3279 | WP_226521553.1 | ATP-binding protein | - |
| LHJ73_RS10580 (LHJ73_10580) | 2217359..2218498 | + | 1140 | WP_226521554.1 | DUF3322 domain-containing protein | - |
| LHJ73_RS10585 (LHJ73_10585) | 2218481..2218882 | - | 402 | WP_226521555.1 | PIN domain nuclease | Toxin |
| LHJ73_RS10590 (LHJ73_10590) | 2218879..2219082 | - | 204 | WP_226521556.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| LHJ73_RS10595 (LHJ73_10595) | 2219681..2223010 | - | 3330 | WP_207546857.1 | Swt1 family HEPN domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 14846.98 Da Isoelectric Point: 5.6122
>T219217 WP_226521555.1 NZ_CP084713:c2218882-2218481 [Mycolicibacterium phocaicum]
MILVDTSAWIEFLRNTGSSVCERVDELLAEPIAICAPVQMEILAGARNDRHLKDLRGLLARAQTLPTSPTDYEDAAAIYR
VCRRRGETVRKLIDCLIAAHAIREQIPILHSDSDFDAIARHTSLQLDTSPRPD
MILVDTSAWIEFLRNTGSSVCERVDELLAEPIAICAPVQMEILAGARNDRHLKDLRGLLARAQTLPTSPTDYEDAAAIYR
VCRRRGETVRKLIDCLIAAHAIREQIPILHSDSDFDAIARHTSLQLDTSPRPD
Download Length: 402 bp
>T219217 NZ_CP116214:c57545-57237 [Klebsiella michiganensis]
ATGCAGTATTACGTTTATAAGAATACAGGTCGAATTGCTGCGTATCCTTACCTCCTTGATGTACAGAGTGACATTATCGG
CAAGCGCAATACTCGGGTCGTGATTCCACTGTTTCCACTGAAAAACTATAAAGGTCCACGCGCCGATCGTTTAACACCGC
TTGTCACCGTAGAAGGGGAAGAATACGTCGTGATGACTCACGAACTCGCCAGTATCCCACATCGTGTTCTGGGTGAAGAA
GTTTGTAATCTGAATCACCAGCGCGAAGTCGTTAAAGCTTCAATGGATTTTCTTTTCGACGGGATCTAA
ATGCAGTATTACGTTTATAAGAATACAGGTCGAATTGCTGCGTATCCTTACCTCCTTGATGTACAGAGTGACATTATCGG
CAAGCGCAATACTCGGGTCGTGATTCCACTGTTTCCACTGAAAAACTATAAAGGTCCACGCGCCGATCGTTTAACACCGC
TTGTCACCGTAGAAGGGGAAGAATACGTCGTGATGACTCACGAACTCGCCAGTATCCCACATCGTGTTCTGGGTGAAGAA
GTTTGTAATCTGAATCACCAGCGCGAAGTCGTTAAAGCTTCAATGGATTTTCTTTTCGACGGGATCTAA
Antitoxin
Download Length: 68 a.a. Molecular weight: 7654.60 Da Isoelectric Point: 6.4547
>AT219217 WP_226521556.1 NZ_CP084713:c2219082-2218879 [Mycolicibacterium phocaicum]
MTRTNIDIDDHACEVVMRRFHLTSKRDAVNFALRNLAQEALDLKAARGLRGSGWDADLDELRSDRVQ
MTRTNIDIDDHACEVVMRRFHLTSKRDAVNFALRNLAQEALDLKAARGLRGSGWDADLDELRSDRVQ
Download Length: 204 bp
>AT219217 NZ_CP116214:c57784-57548 [Klebsiella michiganensis]
ATGCCAGCCGCAAAACGCAATAAGCAGAACGTCAGCGTGACACTGGACCCAGGCCTGGTCAAACAGGCTCGTGAGGTCGG
CATCAATCTGTCTCTAACGTTGACTAACGCTCTAAAAAGCGAAATCCACAGCCTCGAAATAGCCCGCTGGCAAAAAGAAA
ATGCCCAGGCAATCGACTACCTCAATAATTTAACTGAGGAAAATGGACTTCTCTCTGATGAATACAGGACGTTCTAA
ATGCCAGCCGCAAAACGCAATAAGCAGAACGTCAGCGTGACACTGGACCCAGGCCTGGTCAAACAGGCTCGTGAGGTCGG
CATCAATCTGTCTCTAACGTTGACTAACGCTCTAAAAAGCGAAATCCACAGCCTCGAAATAGCCCGCTGGCAAAAAGAAA
ATGCCCAGGCAATCGACTACCTCAATAATTTAACTGAGGAAAATGGACTTCTCTCTGATGAATACAGGACGTTCTAA