Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-VagC |
| Location | 4562688..4563364 | Replicon | chromosome |
| Accession | NC_008786 | ||
| Organism | Verminephrobacter eiseniae EF01-2 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | VEIS_RS20080 | Protein ID | WP_011811839.1 |
| Coordinates | 4562960..4563364 (+) | Length | 135 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | VEIS_RS20075 | Protein ID | WP_041951093.1 |
| Coordinates | 4562688..4562963 (+) | Length | 92 a.a. |
Genomic Context
Location: 4559168..4559362 (195 bp)
Type: Others
Protein ID: WP_157048609.1
Type: Others
Protein ID: WP_157048609.1
Location: 4560067..4562337 (2271 bp)
Type: Others
Protein ID: WP_011811837.1
Type: Others
Protein ID: WP_011811837.1
Location: 4562455..4562706 (252 bp)
Type: Others
Protein ID: WP_157048610.1
Type: Others
Protein ID: WP_157048610.1
Location: 4562688..4562963 (276 bp)
Type: Antitoxin
Protein ID: WP_041951093.1
Type: Antitoxin
Protein ID: WP_041951093.1
Location: 4562960..4563364 (405 bp)
Type: Toxin
Protein ID: WP_011811839.1
Type: Toxin
Protein ID: WP_011811839.1
Location: 4563582..4564841 (1260 bp)
Type: Others
Protein ID: WP_041951094.1
Type: Others
Protein ID: WP_041951094.1
Location: 4564906..4566357 (1452 bp)
Type: Others
Protein ID: WP_011811841.1
Type: Others
Protein ID: WP_011811841.1
Location: 4566371..4567852 (1482 bp)
Type: Others
Protein ID: WP_041951095.1
Type: Others
Protein ID: WP_041951095.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VEIS_RS29175 | 4559168..4559362 | + | 195 | WP_157048609.1 | hypothetical protein | - |
| VEIS_RS20070 | 4560067..4562337 | + | 2271 | WP_011811837.1 | membrane protein | - |
| VEIS_RS29180 | 4562455..4562706 | + | 252 | WP_157048610.1 | hypothetical protein | - |
| VEIS_RS20075 | 4562688..4562963 | + | 276 | WP_041951093.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| VEIS_RS20080 | 4562960..4563364 | + | 405 | WP_011811839.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| VEIS_RS20085 | 4563582..4564841 | - | 1260 | WP_041951094.1 | Zn-dependent hydrolase | - |
| VEIS_RS20090 | 4564906..4566357 | - | 1452 | WP_011811841.1 | dihydropyrimidinase | - |
| VEIS_RS20095 | 4566371..4567852 | - | 1482 | WP_041951095.1 | NCS1 family nucleobase:cation symporter-1 | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 135 a.a. Molecular weight: 14452.73 Da Isoelectric Point: 6.9527
>T21921 WP_011811839.1 NC_008786:4562960-4563364 [Verminephrobacter eiseniae EF01-2]
MSGYLLDTNIISDVIRNPNGPAARRIEQAGPKQIFTSIIVAAELRYGCAKKGSPQLLARVEGLLETVPVLPLDIPADAGY
GGIRAELEAAGQSIGMNDLLIAAHACALGLTLVTDNTREFSRIRKLKVENWLER
MSGYLLDTNIISDVIRNPNGPAARRIEQAGPKQIFTSIIVAAELRYGCAKKGSPQLLARVEGLLETVPVLPLDIPADAGY
GGIRAELEAAGQSIGMNDLLIAAHACALGLTLVTDNTREFSRIRKLKVENWLER
Download Length: 405 bp
>T21921 NC_008786:4562960-4563364 [Verminephrobacter eiseniae EF01-2]
TTGAGCGGATATCTGCTGGACACGAACATCATCAGCGATGTGATCCGCAACCCGAACGGGCCTGCGGCACGTCGCATCGA
GCAAGCCGGGCCGAAGCAGATTTTCACCAGCATCATCGTCGCAGCCGAACTGCGCTATGGCTGCGCAAAGAAGGGTTCGC
CCCAGCTGCTCGCCAGGGTGGAAGGCTTGCTCGAAACGGTCCCGGTGCTGCCGCTGGATATTCCGGCTGACGCCGGATAT
GGCGGCATTCGCGCTGAGTTGGAGGCGGCGGGACAGTCCATCGGCATGAACGATTTGCTGATCGCCGCGCACGCCTGTGC
GCTCGGCCTCACGCTGGTGACGGACAACACGCGCGAGTTCAGCCGCATCCGCAAGCTCAAGGTAGAGAACTGGCTGGAGA
GATAG
TTGAGCGGATATCTGCTGGACACGAACATCATCAGCGATGTGATCCGCAACCCGAACGGGCCTGCGGCACGTCGCATCGA
GCAAGCCGGGCCGAAGCAGATTTTCACCAGCATCATCGTCGCAGCCGAACTGCGCTATGGCTGCGCAAAGAAGGGTTCGC
CCCAGCTGCTCGCCAGGGTGGAAGGCTTGCTCGAAACGGTCCCGGTGCTGCCGCTGGATATTCCGGCTGACGCCGGATAT
GGCGGCATTCGCGCTGAGTTGGAGGCGGCGGGACAGTCCATCGGCATGAACGATTTGCTGATCGCCGCGCACGCCTGTGC
GCTCGGCCTCACGCTGGTGACGGACAACACGCGCGAGTTCAGCCGCATCCGCAAGCTCAAGGTAGAGAACTGGCTGGAGA
GATAG
Antitoxin
Download Length: 92 a.a. Molecular weight: 10346.06 Da Isoelectric Point: 5.8720
>AT21921 WP_041951093.1 NC_008786:4562688-4562963 [Verminephrobacter eiseniae EF01-2]
MPAPLLTPSRPKEAKLFRNNRSQAVRIPVEFELPGDRVMIHREGSKLIVEPVTRPTNIVELLAEWRKEAPLGPEDQLLAI
PDMPARPEDIF
MPAPLLTPSRPKEAKLFRNNRSQAVRIPVEFELPGDRVMIHREGSKLIVEPVTRPTNIVELLAEWRKEAPLGPEDQLLAI
PDMPARPEDIF
Download Length: 276 bp
>AT21921 NC_008786:4562688-4562963 [Verminephrobacter eiseniae EF01-2]
ATGCCTGCCCCCCTGTTGACGCCATCCAGGCCCAAAGAGGCCAAGCTGTTTCGCAACAACCGCAGCCAGGCGGTGCGGAT
TCCTGTGGAGTTCGAGTTGCCCGGGGATCGTGTGATGATCCACCGCGAAGGCAGCAAACTCATCGTCGAGCCAGTGACCC
GGCCAACGAACATCGTCGAACTACTGGCCGAGTGGAGGAAGGAAGCACCGCTTGGGCCAGAAGATCAGTTGTTGGCCATT
CCTGACATGCCCGCCCGGCCGGAGGACATATTTTGA
ATGCCTGCCCCCCTGTTGACGCCATCCAGGCCCAAAGAGGCCAAGCTGTTTCGCAACAACCGCAGCCAGGCGGTGCGGAT
TCCTGTGGAGTTCGAGTTGCCCGGGGATCGTGTGATGATCCACCGCGAAGGCAGCAAACTCATCGTCGAGCCAGTGACCC
GGCCAACGAACATCGTCGAACTACTGGCCGAGTGGAGGAAGGAAGCACCGCTTGGGCCAGAAGATCAGTTGTTGGCCATT
CCTGACATGCCCGCCCGGCCGGAGGACATATTTTGA