Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3162471..3162616 Replicon chromosome
Accession NZ_CP084705
Organism Klebsiella pneumoniae strain KP1064WHY

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3162507..3162609 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3162471..3162616 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8U55_RS15410 (K8U55_15405) 3157601..3159661 + 2061 WP_004151449.1 oligopeptidase B -
K8U55_RS15415 (K8U55_15410) 3159665..3160324 - 660 WP_002911407.1 exodeoxyribonuclease X -
K8U55_RS15420 (K8U55_15415) 3160403..3160633 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K8U55_RS15425 (K8U55_15420) 3160746..3161120 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K8U55_RS15430 (K8U55_15425) 3161124..3161993 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K8U55_RS15435 (K8U55_15430) 3162010..3162348 + 339 WP_002911404.1 YebY family protein -
- 3162471..3162616 - 146 - - Antitoxin
- 3162507..3162609 + 103 - - Toxin
K8U55_RS15440 (K8U55_15435) 3162984..3163127 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K8U55_RS15445 (K8U55_15440) 3163232..3164200 - 969 WP_004151446.1 VirK/YbjX family protein -
K8U55_RS15450 (K8U55_15445) 3164357..3165010 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K8U55_RS15455 (K8U55_15450) 3165007..3165198 - 192 WP_002911395.1 YebW family protein -
K8U55_RS15460 (K8U55_15455) 3165296..3165535 - 240 WP_002911393.1 YebV family protein -
K8U55_RS15465 (K8U55_15460) 3165653..3167087 - 1435 Protein_2999 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219191 NZ_CP084705:3162507-3162609 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219191 NZ_CP084705:c3162616-3162471 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References