Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3842465..3843144 Replicon chromosome
Accession NC_008786
Organism Verminephrobacter eiseniae EF01-2

Toxin (Protein)


Gene name vapC Uniprot ID A1WNI8
Locus tag VEIS_RS16845 Protein ID WP_011811187.1
Coordinates 3842465..3842890 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A1WNI9
Locus tag VEIS_RS16850 Protein ID WP_011811188.1
Coordinates 3842887..3843144 (-) Length 86 a.a.

Genomic Context

VEIS_RS16810VEIS_RS16815VEIS_RS16830VEIS_RS16835VEIS_RS16820VEIS_RS29830VEIS_RS29835VEIS_RS28940VEIS_RS28945VEIS_RS16840VEIS_RS16845VEIS_RS16850VEIS_RS16855VEIS_RS16860VEIS_RS16865VEIS_RS16870
Location: 3837825..3838499 (675 bp)
Type: Others
Protein ID: WP_049773948.1
Location: 3838508..3839500 (993 bp)
Type: Others
Protein ID: WP_011811179.1
Location: 3841239..3841589 (351 bp)
Type: Others
Protein ID: WP_011811183.1
Location: 3841586..3841879 (294 bp)
Type: Others
Protein ID: WP_041950120.1
Location: 3839510..3840130 (621 bp)
Type: Others
Protein ID: WP_041950963.1
Location: 3840508..3840786 (279 bp)
Type: Others
Protein ID: WP_198137881.1
Location: 3840750..3841169 (420 bp)
Type: Others
Protein ID: WP_011811182.1
Location: 3841890..3842036 (147 bp)
Type: Others
Protein ID: WP_157048554.1
Location: 3842040..3842198 (159 bp)
Type: Others
Protein ID: WP_157048555.1
Location: 3842292..3842483 (192 bp)
Type: Others
Protein ID: WP_041950121.1
Location: 3842465..3842890 (426 bp)
Type: Toxin
Protein ID: WP_011811187.1
Location: 3842887..3843144 (258 bp)
Type: Antitoxin
Protein ID: WP_011811188.1
Location: 3843334..3844395 (1062 bp)
Type: Others
Protein ID: WP_011811189.1
Location: 3844778..3845959 (1182 bp)
Type: Others
Protein ID: WP_011811190.1
Location: 3845988..3846716 (729 bp)
Type: Others
Protein ID: WP_011811191.1
Location: 3846713..3847462 (750 bp)
Type: Others
Protein ID: WP_011811192.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VEIS_RS168103837825..3838499+675WP_049773948.1retroviral-like aspartic protease family protein-
VEIS_RS168153838508..3839500+993WP_011811179.1hypothetical protein-
VEIS_RS168203839510..3840130-621WP_041950963.1glycerol-3-phosphate 1-O-acyltransferase PlsY-
VEIS_RS298303840508..3840786-279WP_198137881.1replication initiator protein A-
VEIS_RS298353840750..3841169-420WP_011811182.1replication initiator protein A-
VEIS_RS168303841239..3841589+351WP_011811183.1type II toxin-antitoxin system RelE/ParE family toxin-
VEIS_RS168353841586..3841879+294WP_041950120.1XRE family transcriptional regulator-
VEIS_RS289403841890..3842036-147WP_157048554.1hypothetical protein-
VEIS_RS289453842040..3842198-159WP_157048555.1hypothetical protein-
VEIS_RS168403842292..3842483-192WP_041950121.1hypothetical protein-
VEIS_RS168453842465..3842890-426WP_011811187.1type II toxin-antitoxin system VapC family toxinToxin
VEIS_RS168503842887..3843144-258WP_011811188.1plasmid stability protein stbCAntitoxin
VEIS_RS168553843334..3844395-1062WP_011811189.1aldo/keto reductase-
VEIS_RS168603844778..3845959-1182WP_011811190.1cystathionine beta-lyase-
VEIS_RS168653845988..3846716-729WP_011811191.1amino acid ABC transporter ATP-binding protein-
VEIS_RS168703846713..3847462-750WP_011811192.1amino acid ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15336.59 Da        Isoelectric Point: 4.5626

>T21918 WP_011811187.1 NC_008786:c3842890-3842465 [Verminephrobacter eiseniae EF01-2]
MIVLDTNVISELWKVNPDSNVLAWIDAQAIETLYLSAVTVAELRYGLATMPEGKRRTIYQQRLEDEVLPNFAGRVLAFDL
DMSKTYAELMARARAGGKAIAKADGYIAATAAAHGLIVATRDTSPFEAGGLQVIDPWEALP

Download         Length: 426 bp

>T21918 NC_008786:c3842890-3842465 [Verminephrobacter eiseniae EF01-2]
ATGATCGTCCTCGATACCAACGTCATTTCCGAGTTGTGGAAGGTTAACCCGGATTCCAACGTGCTGGCGTGGATCGATGC
TCAGGCTATTGAAACGCTCTATCTGTCTGCCGTTACGGTCGCAGAGCTGCGCTATGGCCTTGCGACGATGCCCGAGGGCA
AGCGCCGCACGATCTACCAACAACGGCTAGAGGATGAGGTTTTGCCGAACTTCGCCGGCCGCGTGCTGGCCTTCGACCTG
GACATGTCCAAGACCTATGCCGAGCTGATGGCGCGGGCCAGGGCAGGGGGCAAAGCCATCGCCAAGGCAGACGGCTACAT
CGCGGCCACGGCCGCCGCGCACGGCCTGATAGTGGCGACACGCGACACCAGCCCATTTGAGGCCGGAGGGCTTCAGGTCA
TCGACCCTTGGGAGGCTTTGCCGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9514.78 Da        Isoelectric Point: 6.9910

>AT21918 WP_011811188.1 NC_008786:c3843144-3842887 [Verminephrobacter eiseniae EF01-2]
MANVHVRNLPDAVHRALRVRAAHHGRSTEAEIRDILEIATRPPERVKLGSLLASIAREAGGLTDEEHALFESVRDRTPAE
PMRFE

Download         Length: 258 bp

>AT21918 NC_008786:c3843144-3842887 [Verminephrobacter eiseniae EF01-2]
ATGGCAAACGTACATGTAAGAAACCTGCCTGATGCCGTGCACCGTGCGCTTCGCGTGCGTGCCGCACATCATGGCCGCAG
CACAGAGGCGGAAATCCGCGACATTCTGGAAATCGCCACCCGGCCGCCCGAGCGCGTCAAGCTGGGTTCCTTGTTGGCAT
CCATCGCCCGCGAGGCGGGCGGCCTGACAGATGAAGAACACGCCCTGTTTGAGAGCGTGCGTGACAGGACGCCGGCCGAG
CCGATGAGGTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA1WNI8

Antitoxin

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Source
ID
Structure
AlphaFold DBA1WNI9

References