Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 688243..688778 Replicon plasmid pRL12
Accession NZ_CP084699
Organism Rhizobium ruizarguesonis strain RCAM 1026

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BSO17_RS33380 Protein ID WP_024319651.1
Coordinates 688503..688778 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I2GF38
Locus tag BSO17_RS33375 Protein ID WP_027688292.1
Coordinates 688243..688503 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSO17_RS33355 (BSO17_33370) 684038..684919 - 882 WP_003549874.1 ABC transporter permease -
BSO17_RS33360 (BSO17_33375) 684931..685749 - 819 WP_024319648.1 ABC transporter ATP-binding protein -
BSO17_RS33365 (BSO17_33380) 685844..686857 - 1014 WP_018072979.1 ABC transporter substrate-binding protein -
BSO17_RS33370 (BSO17_33385) 687211..687939 - 729 WP_024319649.1 FadR/GntR family transcriptional regulator -
BSO17_RS33375 (BSO17_33390) 688243..688503 + 261 WP_027688292.1 ribbon-helix-helix domain-containing protein Antitoxin
BSO17_RS33380 (BSO17_33395) 688503..688778 + 276 WP_024319651.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSO17_RS33385 (BSO17_33400) 688785..689792 - 1008 WP_024319652.1 LacI family DNA-binding transcriptional regulator -
BSO17_RS33390 (BSO17_33405) 690000..691322 + 1323 WP_024319653.1 alpha-L-fucosidase -
BSO17_RS33395 (BSO17_33410) 691373..692596 + 1224 WP_018072986.1 sugar ABC transporter substrate-binding protein -
BSO17_RS33400 (BSO17_33415) 692679..693653 + 975 WP_024319654.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..838366 838366


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10754.45 Da        Isoelectric Point: 10.1520

>T219172 WP_024319651.1 NZ_CP084699:688503-688778 [Rhizobium ruizarguesonis]
MGIKWTSKAASDVARLYDFLTPVDRQAAVRTVRALTAAPARLLEQPRLGERLEEFDPREVRRILVGRCELRYEIQQSMIY
VLRLWHTREDR

Download         Length: 276 bp

>T219172 NZ_CP116194:c1203310-1203092 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9756.97 Da        Isoelectric Point: 4.4964

>AT219172 WP_027688292.1 NZ_CP084699:688243-688503 [Rhizobium ruizarguesonis]
METKVLTAHVPLPLAQKVDQLASRLERSRGWIVKQALTAWIDQEEERRRLTLEALADVDDGNLVEHQSVQAWADSLDSDE
PISLPR

Download         Length: 261 bp

>AT219172 NZ_CP116194:c1203710-1203336 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References