Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 61220..61911 Replicon plasmid pRL12
Accession NZ_CP084699
Organism Rhizobium ruizarguesonis strain RCAM 1026

Toxin (Protein)


Gene name vapC Uniprot ID A0A4Q8ZX68
Locus tag BSO17_RS30490 Protein ID WP_027688184.1
Coordinates 61220..61648 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A4R0AD13
Locus tag BSO17_RS30495 Protein ID WP_017991284.1
Coordinates 61645..61911 (-) Length 89 a.a.

Genomic Context

BSO17_RS30470BSO17_RS30475BSO17_RS30480BSO17_RS30485BSO17_RS30500BSO17_RS30505BSO17_RS30510BSO17_RS30515BSO17_RS30520BSO17_RS30490BSO17_RS30495
Location: 58115..58954 (840 bp)
Type: Others
Protein ID: WP_024319795.1
Location: 59072..59734 (663 bp)
Type: Others
Protein ID: WP_024319796.1
Location: 59741..60400 (660 bp)
Type: Others
Protein ID: WP_024319797.1
Location: 60413..61183 (771 bp)
Type: Others
Protein ID: WP_018480586.1
Location: 62168..62911 (744 bp)
Type: Others
Protein ID: WP_024319799.1
Location: 62915..63700 (786 bp)
Type: Others
Protein ID: WP_024319800.1
Location: 63782..64453 (672 bp)
Type: Others
Protein ID: WP_024319801.1
Location: 64450..65109 (660 bp)
Type: Others
Protein ID: WP_024319802.1
Location: 65087..65812 (726 bp)
Type: Others
Protein ID: WP_024319803.1
Location: 61220..61648 (429 bp)
Type: Toxin
Protein ID: WP_027688184.1
Location: 61645..61911 (267 bp)
Type: Antitoxin
Protein ID: WP_017991284.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BSO17_RS30470 (BSO17_30485)58115..58954+840WP_024319795.1transporter substrate-binding domain-containing protein-
BSO17_RS30475 (BSO17_30490)59072..59734+663WP_024319796.1amino acid ABC transporter permease-
BSO17_RS30480 (BSO17_30495)59741..60400+660WP_024319797.1amino acid ABC transporter permease-
BSO17_RS30485 (BSO17_30500)60413..61183+771WP_018480586.1amino acid ABC transporter ATP-binding protein-
BSO17_RS30490 (BSO17_30505)61220..61648-429WP_027688184.1type II toxin-antitoxin system VapC family toxinToxin
BSO17_RS30495 (BSO17_30510)61645..61911-267WP_017991284.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
BSO17_RS30500 (BSO17_30515)62168..62911+744WP_024319799.1GntR family transcriptional regulator-
BSO17_RS30505 (BSO17_30520)62915..63700+786WP_024319800.1transporter substrate-binding domain-containing protein-
BSO17_RS30510 (BSO17_30525)63782..64453+672WP_024319801.1amino acid ABC transporter permease-
BSO17_RS30515 (BSO17_30530)64450..65109+660WP_024319802.1amino acid ABC transporter permease-
BSO17_RS30520 (BSO17_30535)65087..65812+726WP_024319803.1amino acid ABC transporter ATP-binding protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..838366838366


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-66)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15824.14 Da        Isoelectric Point: 4.7948

>T219170 WP_027688184.1 NZ_CP084699:c61648-61220 [Rhizobium ruizarguesonis]
VRLLLDTNVLSEVTRPRPDAHVLQWLDDLDEDRSFISVVSIAEIRRGVALMESGRKRDALAEWLAQDLPQRFEQRVIPVD
QAVAITWGDLMGLAKRSGRGLSSMGGLIAATAIAHDLTLATRNIKDFESLGIELVDPWIERP

Download         Length: 429 bp

>T219170 NZ_CP116194:728706-729020 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9960.34 Da        Isoelectric Point: 10.0842

>AT219170 WP_017991284.1 NZ_CP084699:c61911-61645 [Rhizobium ruizarguesonis]
MQPSRPEDKSWTVASAKAKLSEVIERAQATPQTIMRNGKPSVVVVSAEEWQRKTARKGTLAEFLMQSPLRGADLDLERQR
DEPRDLQL

Download         Length: 267 bp

>AT219170 NZ_CP116194:728470-728703 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACA
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A4Q8ZX68

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A4R0AD13

References