Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3728776..3729329 Replicon chromosome
Accession NC_008786
Organism Verminephrobacter eiseniae EF01-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag VEIS_RS16275 Protein ID WP_011811071.1
Coordinates 3728776..3729069 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A1WN73
Locus tag VEIS_RS16280 Protein ID WP_011811072.1
Coordinates 3729057..3729329 (-) Length 91 a.a.

Genomic Context

VEIS_RS16240VEIS_RS16245VEIS_RS16250VEIS_RS16255VEIS_RS16260VEIS_RS16265VEIS_RS16285VEIS_RS29805VEIS_RS16290VEIS_RS16295VEIS_RS16305VEIS_RS16310VEIS_RS16230VEIS_RS26600VEIS_RS27800VEIS_RS27805VEIS_RS29795VEIS_RS29800VEIS_RS26615VEIS_RS28900VEIS_RS16275VEIS_RS16280VEIS_RS16300
Location: 3725209..3725472 (264 bp)
Type: Others
Protein ID: WP_041950935.1
Location: 3725459..3725761 (303 bp)
Type: Others
Protein ID: WP_011811064.1
Location: 3726051..3726560 (510 bp)
Type: Others
Protein ID: Protein_3445
Location: 3726595..3726976 (382 bp)
Type: Others
Protein ID: Protein_3446
Location: 3727050..3727382 (333 bp)
Type: Others
Protein ID: WP_083758754.1
Location: 3727379..3727690 (312 bp)
Type: Others
Protein ID: WP_011811068.1
Location: 3729520..3730227 (708 bp)
Type: Others
Protein ID: Protein_3455
Location: 3730234..3730425 (192 bp)
Type: Others
Protein ID: WP_198138058.1
Location: 3730493..3731124 (632 bp)
Type: Others
Protein ID: Protein_3457
Location: 3731117..3731446 (330 bp)
Type: Others
Protein ID: WP_011811074.1
Location: 3731895..3732440 (546 bp)
Type: Others
Protein ID: Protein_3460
Location: 3732747..3733808 (1062 bp)
Type: Others
Protein ID: WP_011811077.1
Location: 3723820..3724167 (348 bp)
Type: Others
Protein ID: WP_011811061.1
Location: 3724133..3724529 (397 bp)
Type: Others
Protein ID: Protein_3440
Location: 3724631..3724795 (165 bp)
Type: Others
Protein ID: Protein_3441
Location: 3724796..3724945 (150 bp)
Type: Others
Protein ID: WP_086014399.1
Location: 3728049..3728234 (186 bp)
Type: Others
Protein ID: Protein_3449
Location: 3728217..3728363 (147 bp)
Type: Others
Protein ID: Protein_3450
Location: 3728391..3728606 (216 bp)
Type: Others
Protein ID: Protein_3451
Location: 3728603..3728776 (174 bp)
Type: Others
Protein ID: WP_011811070.1
Location: 3728776..3729069 (294 bp)
Type: Toxin
Protein ID: WP_011811071.1
Location: 3729057..3729329 (273 bp)
Type: Antitoxin
Protein ID: WP_011811072.1
Location: 3731558..3731893 (336 bp)
Type: Others
Protein ID: Protein_3459
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VEIS_RS162303723820..3724167-348WP_011811061.1helix-turn-helix domain-containing protein-
VEIS_RS266003724133..3724529-397Protein_3440type II toxin-antitoxin system RelE/ParE family toxin-
VEIS_RS278003724631..3724795-165Protein_3441Hin recombinase-
VEIS_RS278053724796..3724945-150WP_086014399.1replication initiation protein-
VEIS_RS162403725209..3725472+264WP_041950935.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
VEIS_RS162453725459..3725761+303WP_011811064.1type II toxin-antitoxin system YafQ family toxin-
VEIS_RS162503726051..3726560+510Protein_3445Tn3 family transposase-
VEIS_RS162553726595..3726976+382Protein_3446hypothetical protein-
VEIS_RS162603727050..3727382+333WP_083758754.1type II toxin-antitoxin system RelE/ParE family toxin-
VEIS_RS162653727379..3727690+312WP_011811068.1putative addiction module antidote protein-
VEIS_RS297953728049..3728234-186Protein_3449hypothetical protein-
VEIS_RS298003728217..3728363-147Protein_3450addiction module antidote protein-
VEIS_RS266153728391..3728606-216Protein_3451transcriptional regulator-
VEIS_RS289003728603..3728776-174WP_011811070.1hypothetical protein-
VEIS_RS162753728776..3729069-294WP_011811071.1type II toxin-antitoxin system RelE/ParE family toxinToxin
VEIS_RS162803729057..3729329-273WP_011811072.1CopG family ribbon-helix-helix proteinAntitoxin
VEIS_RS162853729520..3730227+708Protein_3455recombinase family protein-
VEIS_RS298053730234..3730425+192WP_198138058.1hypothetical protein-
VEIS_RS162903730493..3731124+632Protein_3457ParA family protein-
VEIS_RS162953731117..3731446+330WP_011811074.1hypothetical protein-
VEIS_RS163003731558..3731893-336Protein_3459integrase-
VEIS_RS163053731895..3732440+546Protein_3460site-specific integrase-
VEIS_RS163103732747..3733808+1062WP_011811077.1IS630 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--3708468..373889730429


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10702.20 Da        Isoelectric Point: 5.6218

>T21917 WP_011811071.1 NC_008786:c3729069-3728776 [Verminephrobacter eiseniae EF01-2]
VPQVIVTEGAAEGLERCRRFLAVKAPDAARRAGQAIERQFLLLKTAPDIGPPFPETPELRELVIAFGDSGYVALYHHEPA
DDAVYVLAFRHQKEAGY

Download         Length: 294 bp

>T21917 NC_008786:c3729069-3728776 [Verminephrobacter eiseniae EF01-2]
GTGCCACAAGTAATCGTCACCGAAGGCGCGGCGGAGGGCTTGGAACGATGCCGGCGGTTCCTGGCCGTCAAGGCACCGGA
CGCCGCCAGGCGTGCCGGCCAGGCCATCGAGCGGCAATTCCTGCTGCTGAAGACGGCCCCCGACATTGGCCCGCCGTTCC
CTGAAACGCCCGAGCTGCGCGAGCTGGTGATTGCCTTCGGGGATTCCGGCTACGTGGCCCTGTACCACCACGAACCGGCC
GACGATGCTGTGTATGTTCTGGCCTTCCGGCACCAGAAAGAGGCGGGCTACTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10579.86 Da        Isoelectric Point: 8.0869

>AT21917 WP_011811072.1 NC_008786:c3729329-3729057 [Verminephrobacter eiseniae EF01-2]
MSTSLKIDDTLKGRVQHLASQRRRSPHWIMLEAIQQYVEREEARESFKQEALASWAAYKETGRHLTGQEVRTWLNTWGTN
DERAVPECHK

Download         Length: 273 bp

>AT21917 NC_008786:c3729329-3729057 [Verminephrobacter eiseniae EF01-2]
ATGTCAACGTCTCTCAAGATCGACGATACGCTGAAAGGTCGCGTCCAGCACCTGGCCAGCCAGCGCCGGCGCTCACCCCA
CTGGATCATGCTCGAAGCGATCCAGCAGTACGTCGAGCGCGAAGAAGCCCGCGAGAGCTTCAAGCAGGAAGCCTTGGCAT
CCTGGGCGGCCTACAAGGAAACCGGCCGCCACCTGACCGGCCAGGAAGTTCGCACCTGGTTGAACACCTGGGGCACCAAT
GACGAAAGGGCGGTGCCTGAGTGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA1WN73

References