Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2126697..2127478 Replicon chromosome
Accession NZ_CP084692
Organism Enterobacter mori strain BC01

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag K6742_RS09945 Protein ID WP_108416253.1
Coordinates 2126987..2127478 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag K6742_RS09940 Protein ID WP_042713858.1
Coordinates 2126697..2126990 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6742_RS09925 (K6742_09925) 2123683..2123997 - 315 WP_010435531.1 lipoprotein -
K6742_RS09930 (K6742_09930) 2124173..2124805 + 633 WP_214594620.1 response regulator transcription factor -
K6742_RS09935 (K6742_09935) 2124802..2126580 + 1779 WP_174341545.1 hybrid sensor histidine kinase/response regulator -
K6742_RS09940 (K6742_09940) 2126697..2126990 + 294 WP_042713858.1 DUF1778 domain-containing protein Antitoxin
K6742_RS09945 (K6742_09945) 2126987..2127478 + 492 WP_108416253.1 GNAT family N-acetyltransferase Toxin
K6742_RS09955 (K6742_09955) 2127804..2128517 - 714 WP_108416254.1 DUF554 domain-containing protein -
K6742_RS09960 (K6742_09960) 2128699..2130834 + 2136 WP_174340124.1 ornithine decarboxylase -
K6742_RS09965 (K6742_09965) 2130923..2131615 - 693 WP_108416530.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17531.35 Da        Isoelectric Point: 7.7032

>T219158 WP_108416253.1 NZ_CP084692:2126987-2127478 [Enterobacter mori]
MISAPEPLRAGHILTPFCCGVDSMDNWLKQRAMKNQASGASRTFVCCGSDSNVLAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMILMVTLGDLV
ASI

Download         Length: 492 bp

>T219158 NZ_CP116191:c3970249-3969953 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10941.57 Da        Isoelectric Point: 9.9156

>AT219158 WP_042713858.1 NZ_CP084692:2126697-2126990 [Enterobacter mori]
MPAANTMAVKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQEFLARLDQAPAPN
AALRKTMQTPAPWEREK

Download         Length: 294 bp

>AT219158 NZ_CP116191:c3969951-3969556 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References